Transrektal ultrasonografi eşliğinde yapılan prostat biyopsilerinin retrospektif analizi
Amaç: Transrektal ultrason eşliğinde prostat iğne biyopsisi, prostat kanseri tanısında standart prosedür haline gelmiştir. Biz bu çalışmada prostat hastalıklarının tanısında transrektal iğne biyopsi yönteminin etkinliğini ve histopatolojik sonuçlarını araştırmayı amaçladık.Gereç ve Yöntem: Ocak 2011- Aralık 2014 tarihleri arasında kliniğimizde transrektal ultrason eşliğinde on kor prostat biyopsisi yapılan 643 olgunun yaşları, klinik özellikleri, prostat spesifik antijen PSA seviyeleri ve histopatolojik sonuçları hasta dosyalarından retrospektif olarak değerlendirilerek veriler analiz edilmiştir. Bulgular: Hastaların yaş ortalaması 66.09 ± 7.65 yıl olarak bulundu. Serum prostat spesifik antijen PSA değeri 46,69 ± 410,72 ng / ml idi. Parmakla rektal muayene pozitifliği 175 27.2% hastada mevcuttu. En sık patolojik tanı benign prostat hipertrofisi BPH 313 % 48.7 olarak bulundu. Prostat kanseri, prostatit, prostatik intraepitelyal neoplazi PİN ve atipik small asiner proliferasyon ASAP oranları sırasıyla 139 % 21.6 , 114 % 17.8 , 51 % 7.9 ve 26 % 4 olarak bulundu. Prostat kanseri grubunda ortalama serum PSA düzeyi diğer gruplara göre yüksek bulundu. Prostat kanseri insidansı 65 yaş üzeri hastalarda anlamlı derecede yüksek izlendi.Sonuç: Yüksek PSA seviyesi ve parmakla rektal muayene bulguları olan hastalar prostat kanseri açısından yüksek riskli grup olarak kabul edilmelidir. Transrektal ultrason eşliğinde prostat iğne biyopsisi prostat hastalıklarının malign benign ayrımı açısından güvenli ve etkili bir yöntemdir
Retrospective analysis of transrectal ultrasonography guided prostate biopsy
Objective: Transrectal ultrasound guided prostate needle biopsy has become standard procedure in prostate cancer diagnosis. We aimed to investigate the efficacy of transrectal ultrasound guided prostate needle biopsy on prostatic diseases and review histopathological outcomes.Materials and Methods: Six hundred and forty-three patients were evaluated in our clinic. Transrectal ultrasound guided prostate needle biopsies for suspicious prostate cancer diagnosis were evaluated retrospectively.Results: Mean age of patients was 66.09±7.65, mean serum prostate spesific antigene value 46.69±410.72 ng/mL and digital rectal examination positivity was 175 27.2% . Of the biopsy results 313 48.7% were benign prostatic hypertrophy, 139 21.6% were carcinoma of the prostate, 114 17.8% were prostatitis, 51 7.9% were prostatic intraepithelial neoplasia and 26 4% were atypical small acinar proliferation of prostate, respectively. Mean serum prostate spesific antigene level in carcinoma of the prostate group was statistically significantly higher in other groups. Prostate cancer incidence was statistically significantly high in the older than 65 years group than younger than 65 years group. Conclusions: Patients with elevated prostate spesific antigene and digital rectal examination findings should be considered as high risk group and should be followed closely in terms of prostate cancer and transrectal ultrasound guided prostate needle biopsy is safe and effective procedure for this group of patients who have extend from benign to malign conditions
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