Favre-Racouchot hastalığı olan iki olgu

Favre-Racouchot hastalığı (FRH) solar komedonlar, senil komedonlar ve kistlerle birlikte olan nodüler kutanöz elastozisi tanımlamak için kullanılmaktadır. Etyopato-genezi tam olarak bilinmemekle birlikte ultraviyole rad-yasyon, fiziksel ajanlar ve çok sayıda sigara içiminin predispozan faktör olduğu düşünülmektedir. Histopatolo- jik olarak belirgin solar elastoz bulguları gösterir. Altmışbeş yaşında ve 61 yaşındaki iki erkek hasta poli-kliniğimize yüzlerinde bilateral gruplaşmış siyah renkli açık, dev komedonlar ve sarımsı renkte papul ve nodül-lerle başvurdu. Klinik ve histopatolojik olarak FRH tanısı kondu, topikal tretinoin krem ve cerrahi tedavi başlandı. Olgularımız hastalığın özelliklerini tipik olarak göstermesi nedeniyle bildirilmiş ve literatürler gözden geçirilmiştir.

Report of two cases having Favre-Racouchot disease

Favre-Racouchot Disease (FRD) is the term that is used to describe the nodular cutaneous elastosis together with solar comedones, senile comedones and cysts. There is no known etiopathogenesis but ultraviolet radiation, physical agents and heavily smoking can predispose to the disease. Histopathologically there is prominent solar elastosis. Two male patients that are 65 and 61 years old were referred to our clinic with the complaint of bilaterally groupings of black-colored, open, giant come-dones and yellowish-colored papules and nodules. We diagnoses the two cases with FRD and started both surgical and medical treatment including tretinoin cream. Our cases were reported due to their demonst-rating typical findings of the disease and literature was reviewed.

Kaynakça

1.

Patterson WM, Fox MD, Schwartz RA. Favre-Racouchot disease. Int J Dermatol 2004;43: 167-9. 2.

Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L. Acquired disorders of elastic tissue: Part 1. Increased elastic tissue and solar elastotic syndromes. J Am Acad Dermatol 2004;51: 1-21. 3.

Stefanidou M, Ioannidou D, Tosca A. Unilateral nodular elastosis with cysts and comedones (Favre-Racouchot syndrome). Dermatology 2001; 202: 270-1. 4.

Kaya TI, Tursen U, Yazici AC, Ikizoglu G. A simple open comedone extraction technique for Favre-Racouchot disease. Photodermatol Photoimmunol Photomed 2005;21: 275-7. 5.

Frances C, Boisnic S, Hartmann DJ, Dautzenberg B, Branchet MC, Le Charpentier Y, Robert L. Changes in the elastic tissue of the non-sun-exposed skin of cigarette smokers. Br J Dermatol 1991;125: 43-7. 6.

Kumar P, Marks R. Sebaceous gland hyperplasia and senile comedones: a prevalence study in elderly hospitalized patients. Br J Dermatol 1987;117: 231-6. 7.

Breit S, Flaig MJ, Wolff H, Plewig G. Favre-Racouchot-like disease after radiation therapy. J Am Acad Dermatol 2003;49: 117-9. 8.

Hassounah A, Pierard G. Kerosis and comedones without prominent elastosis in Favre-Racouchot disease. Am J Dermatopathol 1987;9: 15-7. 9.

Sharkey MJ, Keller RA. Favre-Racouchot syndrome: A combined therapeutic approach. Arch Dermatol 1992;128: 615-6.

Kaynak Göster