Mesut ÖKSÜZ, Gürkan GENÇ, OZAN ÖZKAYA, Kenan BEK, Şükrü ARSLAN, Şaban SARIKAYA

Clinical characteristics of urinary tract infections in a tertiary center

Amaç: Bu çalışmanın amacı üriner system enfeksiyonla-rına (ÜSE) zemin hazırlayan ürolojik anormalliklerin tipini ve sıklığını belirleyerek, ÜSE olan farklı anomalilere sahip hastalarda renal parankimal hasar insidansını araştır-maktır. Material ve Metot: 2003 ve 2008 yılları arasında Ondo-kuz Mayıs Üniversitesi Pediatrik Nefroloji Polikliniğine ÜSE nedeniyle başvuran hastalar değerlendirildi. Bulgular: İncelenen 634 hastanın %65,1i kız; %34,9u erkekti. Olguların %30,9unda üst ÜSE mevcuttu. Sekon-der vesikoüreteral reflüsü (VUR) olan hastalarda karşıla-şılan en sık etiyolojik faktör nörojenik mesane ve aşırı aktif mesane idi. Skar oluşumu için 1 yaştan büyük olmak (P=0,001, OR 4,57 (95% CI 2,119,89) ve VUR olması (P=0,001, OR 7,51, 95% CI 4,5-12,5) bağımsız risk faktör-leri olarak tespit edildi. Sonuç: Bu çalışma ÜSE geçiren çocuklarda 1 yaştan büyük ve VURe sahip olmanın renal skar gelişimi için prediktif faktörler olduğu ortaya konmuştur. Akut ve rekürren üriner sistem enfeksiyonlarının erken teşhis ve etkin tedavisi ile skarlaşma insidansı azaltılabilir.

Üçüncü basamak sağlık merkezinde üriner sistem enfeksiyonlarının karakteristikleri

Objective: The aim of this study is to identify the types and incidence of urological anomalies serving as the causative factors for urinary tract infection (UTI), the incidence of renal parenchymal scarring in different abnormalities of the patients having UTI. Material and Method: The patients which referred to Pediatric Nephrology outpatient clinic at Ondokuz Mayis University for UTI between years of 2003 and 2008 were evaluated. Results: 634 patients were analyzed, %65,1 of the cases were girls and %34,9 were boys. %30,9 of the, patients had upper UTI. The most common etiology in patients with secondary vesicoureteral reflux (VUR) was neuro-genic bladder followed by overactive bladder. The age of above 1 year (P=0.001, OR 4.57 (95% CI 2.119.89) and presence of VUR (P=0.001, OR 7.51, 95% CI 4.5-12.5) were found independent factors for scar formation. Conclusions: This study indicates that age above 1 year and VUR are the most predictive variables for the presence of renal scarring in children presented with UTI. A great effort is needed to reduce the incidence of scarring by early diagnosis and effective early mana-gement of acute and recurrent urinary tract infections.

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