Van Kedilerinde Büyümeye Bağlı İskelet Gelişim Bozukluklarının Radyolojik ve Biyokimyasal Tanısı

Bu çalışmada her iki cinsiyetten 20 adet erkek ve 20 adet dişi olmak üzere toplam 40 adet Van kedisi kullanılmıştır. Çalışmaya alınan hayvanların 3 aylıktan itibaren 3’er ay aralıklar ile ekstremite ve vücudun diğer kısımlarının radyolojik muayeneleri gerçekleştirilmiştir. Ayrıca her muayenede kanları alınmıştır. Klinik muayene sonucunda; 3 kedide raşitizma, 2 kedide hipertrofik osteopati, 3 kedide nutrisyonel sekonder hiperparatroidizm olmak üzere toplam 8 Van Kedisinde metabolik kemik hastalıkları ve 8 adetinde de kalça eklemi displazisi tespit edilmiştir. Yapılan biyokimyasal testlerde ortalama Kalsiyum (Ca), Fosfor (P), Magnezyum (Mg) ve Alkelen fosfataz (ALP) konsantrasyonları raşitizmalı hayvanlarda 9.1 mg/dl, 3.6 mg/dl ve 2.3 mg/dl, 200 U/L, hipertrofik osteopatili hayvanlarda 10.9 mg/dl, 8.4 mg/dl ve 2.3 mg/dl, 260 U/L, Nutrisyonel sekonder hiperparatiroidizm (NSH)’lihayvanlarda 8.6 mg/dl, 8.2 mg/dl ve 2.3 mg/dl, 206 U/L olarak tespit edildi. Ca, P oranı raşitizmalı hayvanlarda 2.6 mg/dl, hipertrofik osteopatili hayvanlarda 1.3 mg/dl, nutrisyonel sekonder hiperparatroidizmli hayvanlarda 1.1 mg/dl olarak belirlendi. Sonuç olarak Van Kedilerinde beslenmeye bağlı olarak metabolik kemik hastalıklarının oluştuğu, bu hastalıkların kesin teşhislerinin konulmasında radyolojik ve biyokimyasal sonuçların önem arzettiği, bu yüzden metabolik kemik hastalığı saptanan kedilerde klinik bulguların radyolojik ve biyokimyasal muayenelerle desteklenmesi gerektiği kanısına varılmıştır.

Anahtar Kelimeler:

Alkalenfosfataz, Fosfor, Gelişim bozukluğu, Kalsiyum, Magnezyum, Van Kedisi

Radiological and Biochemical Diagnosis of Skeletal Developmental Disorders Due to Growth in Van Cats

In this study, fourty Van Cats, twenty cats from each gender, were used. Extremities and other parts of the animals' body were examined radiologically at three months intervals, starting from three months old. Besides, in every examination animals' blood test were done. In the conclusion of the clinical examination metabolic bone diseases in eight animals and hip dysplasia in another eight were diagnosed. The distribution of the diseases in animals were as following, rachitism in three cats, hyperthyrophic osteopathy in two and nutritional secondary hyperparathyroidism in three. In biological tests, average concentrations of Calcium (Ca), Phosphorus (P), Magnesium (Mg) and Alkaline Phosphatase (ALP) were 9.1 mg/dl, 3.6 mg/dl and 2.3 mg/dl, 200 U/L in rachitic animals, 10.9 mg/dl, 8.4 mg/dl and 2.3 mg/dl, 260 U/L in animals with hyperthyrophic osteopathy, 8.6 mg/dl, 8.2 mg/dl and 2.3 mg/dl, 206 U/L in animals with nutritional secondary hyperparathyroidism. The ratio of Ca and P was 2.6 mg/dl in rachitic animals, 1.3 mg/dl in animals with hyperthyrophic osteopathy and 1.1 mg/dl in animals with nutritional secondary hyperparathyroidism. As a result, metabolic bone diseases occur depending on nutrition in Van Cats. Radiological and biochemical results are essential in the accurate diagnosis of these diseases. Therefore, for the cats which are diagnosed with metabolic bone disease, clinical findings should be supported with radiological and biochemical examinations.

Keywords:

Alkalinephosphatase, Phosphour, Developing defaults, Calcium, Magnesium, Van Cat,

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