Lokal Hemostatik Ajanlar

Bir organ ya da dokuda meydana gelen kanamanın önlenmesi süreci hemostaz olarak tanımlanır. Hemostaz mekanizmalarında bir bozukluk bulunmayan sağlıklı bireylerde kanama genellikle herhangi bir önlem gerektirmeden kendiliğinden durmaktadır. Geleneksel yöntemlere ek olarak günümüzde kanama kontrolü için bazı yardımcı ajanlar da kullanılmaktadır. Selüloz ya da kollajen içeren ajanlar, sentetik yapıştırıcılar veya fibrin içerikli maddeler bu grubun başında gelmektedir. Kitosan, ankaferd ya da zeolit gibi ajanlarda nispeten daha yeni ajanlar olarak tanımlanmaktadır. Etkinlik ve güvenilirlik açısından bu tip yeni nesil ajanlarda belli başlı soru işaretleri bulunmaktadır. Cerrahi sahanın büyüklüğü, hastanın sistemik durumu, kanama diyatezleri, hastanın kullandığı ilaçlar ya da cerrahi esnasında gelişen komplikasyonlarda lokal hemostatik ajanlar klinisyenin başarısını önemli ölçüde artırmaktadır. Bu derlemede mevcut lokal hemostatik ajanların işlevselliği ve kullanımına bağlı gelişen klinik durumlar incelenmiş, aynı zamanda akılcı kullanımıyla ilgili özellikler, endikasyonlar ve sınırlamalar değerlendirilmiştir

Anahtar Kelimeler:

Hemostatik, Hemostatik ajanlar, Zeolit

Local Hemostatic Agents

The process of preventing bleeding in an organ or tissue is defined as haemostasis. In healthy individuals without a defect in hemostasis mechanisms, bleeding usually stops spontaneously without any measures. In addition to conventional methods, some auxiliary agents are currently used for bleeding control. Cellulose or collagen-containing agents, synthetic adhesives or fibrin-containing substances are at the top of this group. Chitosan is defined as relatively newer agents in agents such as ankaferd or zeolite. In terms of efficiency and reliability, these new generation agents have a number of important question marks. Local haemostatic agents significantly increase the clinician’s success, especially in the size of the surgical site, the patient’s systemic condition, bleeding diathesis, the medication used by the patient, or complications during surgery. In this review, we investigated the clinical status of the local hemostatic agents and the clinical conditions associated with their use; At the same time, features, indications and limitations related to rational use were evaluated

Keywords:

Hemostatic, Hemostatic agents, Zeolite,

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