Sezgin ŞENTÜRK, Meltem ÇETİN, Esin GÖLCÜ, DUYGU UDUM KÜÇÜKŞEN

Akut ve kronik böbrek yetmezliğine sahip köpeklerde lipid profilinin değerlendirilmesi

İnsanlarda serum lipid ve lipoprotein konsantrasyonları böbrek yetmezliği ile ilişkilendirilmiştir. Bu çalışmada total kolesterol, trigliserid, HDL-C, LDL-C'yi kapsayan serum lipidleri ile böbrek yetmezlikleri (akut ve kronik renal yetmezlik) arasındaki ilişkinin araştırılması amaçlanmıştır. Kronik böbrek yetmezliğine sahip olan köpeklerin akut renal yetmezlikli ve sağlıklı köpeklerle karşılaştırılmasında, serum total kolesterol, trigliserid ve LDL-C seviyelerinin istatiksel olarak daha yüksek düzeyde olduğu bulundu (p

Anahtar Kelimeler:

triyosilgliserol, kolesterol, kan lipitleri, köpek, böbrek yetmezliği, düşük yoğunluklu lipoprotein, yüksek yoğunluklu lipoprotein, kan kimyası

Evaluation of lipid in dogs with acute and chronic renal failure

Serum lipids and lipoprotein concentrations have been associated with renal failure in humans. The aim of this study was to investigate the link between serum lipids, including total cholesterol, triglyceride, HDL-C, LDL-C and renal failure (acute renal failure or chronic renal failure) in dogs. Levels of serum total cholesterol, triglycerides and LDL-C statistically significantly higher in dogs with chronic renal failure compared to healty dogs and dogs with acute renal failure (p<0.001). However, levels of serum HDL-C sig-nificantly was lower in dogs with chronic renal failure (CRF) than in dogs with acute renal failure and healty dogs (p<0.001). As a result, it was determined that relation was existed between serum lipids, including total cholesterol, triglyceride, HDL-C, LDL-C, and CRF in dogs.

Keywords:

triacylglycerols, cholesterol, blood lipids, dogs, renal failure, low density lipoprotein, high density lipoprotein, blood chemistry,

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