Kerem URAL, Mehmet Çağrı KARAKURUM, Özkan DURU, Cenker Çağrı CINGI

Serum zinc concentrations in dogs with Microsporum canis dermatophytosis: a pilot study

Zinc deficiency may result in alopecia, erythema, crusting, scaling, parakeratosis, inflammation of the skin, and impaired wound healing. Zinc deficiency also may impair the immune response against microorganisms and lead to fungal infections such as trichophytosis. The present study included male and female dogs (n = 7) of various breeds, ages, and diagnosed with Microsporum canis dermatophytosis and 4 healthy dogs used as the control group. The influence of dermatophytosis on serum zinc concentrations in dogs was investigated. Wood's lamp examination, fungal cultures, and additionally biopsy specimen were used to confirm the diagnosis and rule out other causes of the skin lesions. Serum zinc concenrations were determined by use of an atomic absorption spectrophotometer. No statistical difference was found in zinc concentrations between the dogs with dermatophytosis and normal dogs. Based upon the findings of this pilot study, no association was documented between the occurrence of dermatophytosis and the serum zinc concentrations.

Anahtar Kelimeler:

Key words: Serum zinc concentrations, dermatophytosis, dog

Serum zinc concentrations in dogs with Microsporum canis dermatophytosis: a pilot study

Keywords:

Key words: Serum zinc concentrations, dermatophytosis, dog,

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Scott, D.W., Miller, W.H., Griffin, C.E.: Fungal skin diseases. In: Muller and Kirk’s Small Animal Dermatology. 6thedn., W.B. Saunders, Philadelphia. 2005; 329-391. 2. Foil, C.S.: Dermatophytosis. In: Greene, C.E., Ed., Infectious Diseases of the Dog and Cat. W.B. Saunders, Philadelphia. 1998; 362-370. 3.
Moriello, K.A.: Treatment of dermatophytosis in dogs and cats:
review of published studies. Vet. Dermatol., 2004; 15: 99-107. 4.
Pond, W.G., Church, D.C., Pond, K.R.: Inorganic mineral
elements. In: Basic Animal Nutrition and Feeding. 4thedn. John
Ohlen, B., Scott, D.W.: Zinc-responsive dermatitis in puppies. Canine Pract., 1986; 13: 6-10.
Jezyk, P.F., Haskins, M.E., MacKay-Smith, W.E., Patterson, D.F.: Lethal acrodermatitis in bull terriers. J. Am. Vet. Med. Assoc., 1986; 188: 833-839.
Colombini, S., Dunstan, R.W.: Zinc-responsive dermatosis in northern-breed dogs: 17 cases (1990-1996). J. Am. Vet. Med. Assoc., 1997; 211: 451-453.
Van Wouwe, J.P.: Clinical and laboratory diagnosis of acrodermatitis enteropathica. Eur. J. Pediatr., 1989; 149: 2-8.
Nelson, D.R.,Wolff, W.A., Blodgett, D.J., Luecke, B., Ely, R.W., Zachary, J.F.: Zinc deficiency in sheep and goats: three field cases. J. Am. Vet. Med. Assoc., 1984; 184: 1480-1485.
Schlerka, G., Baumgartner, W.: Parakeratose bei einem Höhenfleckviehkalb. Wien. Tierarztl. Monat., 1976; 63: 19-22.
Suliman, H.B., Abdelrahim, A.I, Zakia, A.M., Shommein, A.M.: Zinc deficiency in sheep: field cases. Trop. Anim. Health Prod., 1988; 20: 47-51.
Krametter-Froetscher, R., Hauser, S., Baumgartner, W.: Zinc- responsive dermatosis in goats suggestive of hereditary malabsorption: two field cases. Vet. Dermatol., 2005; 16: 269- 275.
Pierson, R.E.: Zinc deficiency in young lambs. J. Am. Vet. Med. Assoc., 1966; 149: 1279-1282.
Clauss, M., Lendl, C., Schramel, P., Streich, W.J.: Skin lesions in alpacas and llamas with low zinc and copper status-a preliminary report. Vet. J., 2004; 167: 302-305.
Vogt, D.W., Carlton, C.G., Miller, R.B.: Hereditary parakeratosis in shorthorn beef calves. Am. J. Vet. Res., 1988: 49; 120-121.
O’Brien, J.K.: Inherited parakeratosis in two Frisian calves. Vet. Rec., 1986; 119: 206-207.
Fraker, P.J., Gershwin, M.E., Good, R.A., Prasad, A.: Interrelationships between zinc and immune function. Fed. Proc., 1986; 45: 1474-1479.
Prasad, A.S.: Clinical, endocrinological and biochemical effects of zinc deficiency. Clin. Endocrinol. Metab., 1985; 14: 567-589.
Ogawa, H., Summerbell, R.C., Clemons, K.V., Koga, T., Ran, Y.P., Rashid, A., Sohnle, P.G., Stevens, D.A., Tsuboi, R.: Dermatophytes and host defence in cutaneous mycoses. Med. Mycol., 1998; 36 (Suppl. 1): 166-173.