Yongqing JIANG, Junfang JIANG, Zhigang ZHU, Zirong XU

Postnatal expression pattern of PPARy gene in pigs

PPARγ is a member of the peroxisome proliferator-activated receptor subfamily of nuclear hormone receptors. PPARγ has been showed to be a key regulator of adipocyte differentiation and lipid metabolism. The pattern of PPARγ gene expression in different growth stages and its relation with adipose deposition in pigs is studied. Fifteen female Duroc×Landrace×Yorkshire pigs in 5 groups with 3 pigs in each grup, at live weight of 1, 30, 50, 70, and 90 kg were used to study the developmental gene expression of PPARγ in subcutaneous adipose tissue by means of semi-quantitative RTPCR. The results showed the PPARγ mRNA levels of porcine adipose tissue increased as pigs grew and deposited fat from 1 to 90 kg live weight (P < 0.05). The present data indicated a close positive correlation between the levels of PPARγ gene expression and the fat deposition rate in pigs. The experiment showed the total adipose weight increased significantly with body weight (P < 0.05).

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