The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity

To investigate whether autonomic nervous system (ANS) hyperactivity may be a potential cause for the relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Materials and methods: Twenty-four patients were recruited for this study. Complete physical examinations, urine analysis, uroflowmetry, and postvoid residual urine volume (PVRU) analysis were performed. The potential impact of some factors such as hyperglycemia, obesity, and hyperlipidemia were analyzed. These values were correlated with the various symptom scores. We performed an electromyographic and an electrocardiographic evaluation. The alterations after treatment with 2 different alpha-blockers were also analyzed. Results: The electromyographic and electrocardiographic assessments revealed a minimal increase in ANS activity and it did not change significantly after treatment (P > 0.05). After treatment, maximum flow rate increased and PVRU decreased significantly (P < 0.001 and P < 0.001, respectively); total and free testosterone levels increased significantly (P = 0.0068 and P = 0.0071, respectively). There was a statistically significant difference between the 2 treatment groups regarding the outcomes of the Danish Prostate Symptom Score questionnaire (P = 0.047). Conclusion: This current study suggested that the effect of ANS hyperactivity is not the fundamental factor underlying the relationship between LUTS and ED.

The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity

To investigate whether autonomic nervous system (ANS) hyperactivity may be a potential cause for the relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Materials and methods: Twenty-four patients were recruited for this study. Complete physical examinations, urine analysis, uroflowmetry, and postvoid residual urine volume (PVRU) analysis were performed. The potential impact of some factors such as hyperglycemia, obesity, and hyperlipidemia were analyzed. These values were correlated with the various symptom scores. We performed an electromyographic and an electrocardiographic evaluation. The alterations after treatment with 2 different alpha-blockers were also analyzed. Results: The electromyographic and electrocardiographic assessments revealed a minimal increase in ANS activity and it did not change significantly after treatment (P > 0.05). After treatment, maximum flow rate increased and PVRU decreased significantly (P < 0.001 and P < 0.001, respectively); total and free testosterone levels increased significantly (P = 0.0068 and P = 0.0071, respectively). There was a statistically significant difference between the 2 treatment groups regarding the outcomes of the Danish Prostate Symptom Score questionnaire (P = 0.047). Conclusion: This current study suggested that the effect of ANS hyperactivity is not the fundamental factor underlying the relationship between LUTS and ED.

Kaynakça

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Kaynak Göster

Bibtex @ { tbtkmedical146682, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2014}, volume = {44}, pages = {681 - 686}, doi = {10.3906/sag-1304-122}, title = {The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity}, key = {cite}, author = {Umul, Mehmet and Altay, Ahmet Barış and Bademkıran, Fikret and Turna, Burak} }
APA Umul, M , Altay, A , Bademkıran, F , Turna, B . (2014). The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity . Turkish Journal of Medical Sciences , 44 (4) , 681-686 . DOI: 10.3906/sag-1304-122
MLA Umul, M , Altay, A , Bademkıran, F , Turna, B . "The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity" . Turkish Journal of Medical Sciences 44 (2014 ): 681-686 <
Chicago Umul, M , Altay, A , Bademkıran, F , Turna, B . "The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity". Turkish Journal of Medical Sciences 44 (2014 ): 681-686
RIS TY - JOUR T1 - The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity AU - Mehmet Umul , Ahmet Barış Altay , Fikret Bademkıran , Burak Turna Y1 - 2014 PY - 2014 N1 - doi: 10.3906/sag-1304-122 DO - 10.3906/sag-1304-122 T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 681 EP - 686 VL - 44 IS - 4 SN - 1300-0144-1303-6165 M3 - doi: 10.3906/sag-1304-122 UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity %A Mehmet Umul , Ahmet Barış Altay , Fikret Bademkıran , Burak Turna %T The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity %D 2014 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 44 %N 4 %R doi: 10.3906/sag-1304-122 %U 10.3906/sag-1304-122
ISNAD Umul, Mehmet , Altay, Ahmet Barış , Bademkıran, Fikret , Turna, Burak . "The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity". Turkish Journal of Medical Sciences 44 / 4 (Mayıs 2014): 681-686 .
AMA Umul M , Altay A , Bademkıran F , Turna B . The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity. Turkish Journal of Medical Sciences. 2014; 44(4): 681-686.
Vancouver Umul M , Altay A , Bademkıran F , Turna B . The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity. Turkish Journal of Medical Sciences. 2014; 44(4): 681-686.
IEEE M. Umul , A. Altay , F. Bademkıran ve B. Turna , "The relationship between lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: the role of autonomic hyperactivity", Turkish Journal of Medical Sciences, c. 44, sayı. 4, ss. 681-686, May. 2014, doi:10.3906/sag-1304-122
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

25.2b 24.3b

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