Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis

To compare the differences in clinical characteristics and disease impact on life between patients with juvenile-onset ankylosing spondylitis (JoAS) and patients with adult-onset AS (AoAS). Materials and methods: Demographic and clinical data were collected from 139 AS patients. Disease activity was defined with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Functional status was assessed with the Bath Ankylosing Spondylitis Functional Index (BASFI). Status of quality of life was evaluated with the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire. Results: There were 50 patients with JoAS (36.0%) and 89 with AoAS (64.0%). The JoAS group showed more onset with peripheral joints involvement (P < 0.001), significant diagnosis delay (P < 0.001), worse functional status (P = 0.002), and poorer quality of life (P = 0.002). Patients with JoAS also showed a significantly lower rate in college education (P = 0.037) and marriage (P = 0.013). The rate of employment in the JoAS group was lower than that in the AoAS group. Although the difference in employment did not reach a significant level, the JoAS group included more patients who had not been employed since reaching adulthood (P = 0.015). Conclusion: Compared to patients with AoAS, patients with JoAS may need more specific clinical interventions as well as social assistance.

Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis

To compare the differences in clinical characteristics and disease impact on life between patients with juvenile-onset ankylosing spondylitis (JoAS) and patients with adult-onset AS (AoAS). Materials and methods: Demographic and clinical data were collected from 139 AS patients. Disease activity was defined with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Functional status was assessed with the Bath Ankylosing Spondylitis Functional Index (BASFI). Status of quality of life was evaluated with the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire. Results: There were 50 patients with JoAS (36.0%) and 89 with AoAS (64.0%). The JoAS group showed more onset with peripheral joints involvement (P < 0.001), significant diagnosis delay (P < 0.001), worse functional status (P = 0.002), and poorer quality of life (P = 0.002). Patients with JoAS also showed a significantly lower rate in college education (P = 0.037) and marriage (P = 0.013). The rate of employment in the JoAS group was lower than that in the AoAS group. Although the difference in employment did not reach a significant level, the JoAS group included more patients who had not been employed since reaching adulthood (P = 0.015). Conclusion: Compared to patients with AoAS, patients with JoAS may need more specific clinical interventions as well as social assistance.

Kaynakça

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Kaynak Göster

Bibtex @ { tbtkmedical146669, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2014}, volume = {44}, pages = {601 - 605}, doi = {10.3906/sag-1306-64}, title = {Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis}, key = {cite}, author = {Guan, Mingqiang and Wang, Jian and Zhu, Zhigang and Xıao, Jun and Zhao, Liang and Lı, Zhihan and Shı, Zhanjun} }
APA Guan, M , Wang, J , Zhu, Z , Xıao, J , Zhao, L , Lı, Z , Shı, Z . (2014). Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis . Turkish Journal of Medical Sciences , 44 (4) , 601-605 . DOI: 10.3906/sag-1306-64
MLA Guan, M , Wang, J , Zhu, Z , Xıao, J , Zhao, L , Lı, Z , Shı, Z . "Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis" . Turkish Journal of Medical Sciences 44 (2014 ): 601-605 <
Chicago Guan, M , Wang, J , Zhu, Z , Xıao, J , Zhao, L , Lı, Z , Shı, Z . "Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis". Turkish Journal of Medical Sciences 44 (2014 ): 601-605
RIS TY - JOUR T1 - Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis AU - Mingqiang Guan , Jian Wang , Zhigang Zhu , Jun Xıao , Liang Zhao , Zhihan Lı , Zhanjun Shı Y1 - 2014 PY - 2014 N1 - doi: 10.3906/sag-1306-64 DO - 10.3906/sag-1306-64 T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 601 EP - 605 VL - 44 IS - 4 SN - 1300-0144-1303-6165 M3 - doi: 10.3906/sag-1306-64 UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis %A Mingqiang Guan , Jian Wang , Zhigang Zhu , Jun Xıao , Liang Zhao , Zhihan Lı , Zhanjun Shı %T Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis %D 2014 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 44 %N 4 %R doi: 10.3906/sag-1306-64 %U 10.3906/sag-1306-64
ISNAD Guan, Mingqiang , Wang, Jian , Zhu, Zhigang , Xıao, Jun , Zhao, Liang , Lı, Zhihan , Shı, Zhanjun . "Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis". Turkish Journal of Medical Sciences 44 / 4 (Mayıs 2014): 601-605 .
AMA Guan M , Wang J , Zhu Z , Xıao J , Zhao L , Lı Z , Shı Z . Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis. Turkish Journal of Medical Sciences. 2014; 44(4): 601-605.
Vancouver Guan M , Wang J , Zhu Z , Xıao J , Zhao L , Lı Z , Shı Z . Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis. Turkish Journal of Medical Sciences. 2014; 44(4): 601-605.
IEEE M. Guan , J. Wang , Z. Zhu , J. Xıao , L. Zhao , Z. Lı ve Z. Shı , "Comparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis", Turkish Journal of Medical Sciences, c. 44, sayı. 4, ss. 601-605, May. 2014, doi:10.3906/sag-1306-64
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

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