Ercan YENİ, Hakim ÇELİK, Halil ÇİFTÇİ, Mehmet GÜLÜM, Murat SAVAŞ

Do the applied shock wave numbers and the application side aff ect pancreatic exocrine functions in patients who have undergone extracorporeal shock wave lithotripsy for upper urinary tract calculi?

Amaç: Üst üriner sistem taşları için uygulanan ESWLnin pankreas ekzokrin fonksiyonları üzerindeki etkisinin şok sayısı ile ve ESWL uygulanan böbrek tarafı ile ilişkisini araştırmak. Yöntem ve gereç: Bu prospektif çalışma üst üreter ve böbrek taşları için ESWL uygulanan ardışık 76 hastayı içermektedir. Sağ böbrek taşı nedeniyle ESWL uygulanan 40 hasta sağ böbrek gurubu (RKG), sol böbrek taşı nedeniyle ESWL uygulanan 36 hasta da sol böbrek gurubu (LKG) olarak adlandırıldı. Bulgular: ESWL sonrası serum amilaz ve lipaz değerlerindeki değişiklikler ESWL öncesi değerlerle karşılaştırıldığında istatistiksel olarak anlamlı değildi. Serum amilaz ve lipaz değerleriyle uygulanan şok dalga sayısı arasındaki ilişkiye bakıldığında ise RKGda pozitif korelasyon varken, bu korelasyon LKGda tespit edilmedi. Sonuç: Bu çalışmada, ESWL sonrası serum amilaz ve lipaz değerlerinde istatisiksel olarak anlamlı bir artış bulmadık. Ancak, RKG da uygulanan şutsayısi ile ESWL sonrası serum amilaz ve lipaz değerleri arasında pozitif bir korelasyon gördük. Klinik ve deneysel çalışmalar ESWLnin genel olarak güvenli olduğunu işaret etse de gereğinden fazla seans ve şut sayısısından kaçınmak ESWLnin potansiyel risklerini önlemek için faydalı olabilir.

Üst üriner taş nedeniyle ESWL uygulanan hastalarda uygulama tarafı ve şut sayısı pankreas ekzokrin fonksiyonları etkiler mi?

Aim: To investigate the effect of extracorporeal shock wave lithotripsy (ESWL) on the pancreatic exocrine functions related to the number of high-energy shock waves and the ESWL-applied kidney side for upper urinary tract stones. Materials and methods: Included in the study were 76 patients undergoing ESWL for proximal ureteral or kidney stones. The right kidney group (RKG) consisted of 40 patients who underwent ESWL for right kidney stones and the left kidney group (LKG) consisted of 36 patients who underwent ESWL for left kidney stones. Results: The observed changes in plasma amylase and lipase levels were not statistically signifi cant compared with the pre-ESWL values in both groups. The relationship between the number of applied shock waves (SWs) and the serum amylase and lipase after ESWL showed a statistically signifi cant positive correlation in the RKG but not in the LKG. Conclusion: There were no statistically significant differences between the pre- and post-ESWL serum amylase and lipase levels. However, a statistically significant positive correlation was found between the number of SWs applied and the post-ESWL amylase and lipase levels in the RKG. Although clinical and experimental studies have shown the safety of ESWL, avoiding excess sessions and an unnecessarily high number of SWs may be helpful in the prevention of the potential risks of ESWL.

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