Does the treatment of obstructive sleep apnea syndrome improve lower urinary tract symptoms?

Aim: To evaluate lower urinary tract symptoms in patients with obstructive sleep apnea syndrome (OSAS) and to determine if the symptoms improved after treatment for OSAS. Materials and methods: In all, 145 male patients were diagnosed with OSAS via polysomnography and evaluated for lower urinary tract symptoms using the International Prostate Symptom Score (IPSS). All of the patients were evaluated by an ear, nose, and throat (ENT) specialist. Surgery or continuous positive airway pressure treatment was recommended based on the apnea-hypopnea index (AHI) and ENT examination results. Only 23 of the patients that were available for follow-up during treatment were included in the study. The IPSS form was administered after treatment and symptom scores were updated for the 23 patients. The age range of the 23 patients was 26-65 years. The Wilcoxon signed rank, Kruskal-Wallis, and Spearman rho tests were used to evaluate differences in IPSSs before and after treatment. Results: After treatment, significant improvement in lower urinary tract symptoms was confirmed statistically based on the IPSSs of 23 OSAS patients (P < 0.001). The difference in the IPSS before and after treatment was not associated with the AHI, treatment method, patient age, or body mass index (P > 0.05). Conclusion: Most of the OSAS patients had lower urinary tract symptoms, and significant improvement in these symptoms was observed following treatment for OSAS.

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Key words: Obstructive sleep apnea syndrome, treatment, lower urinary tract symptoms

Does the treatment of obstructive sleep apnea syndrome improve lower urinary tract symptoms?

Keywords:

Key words: Obstructive sleep apnea syndrome, treatment, lower urinary tract symptoms,

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1. Muller JE, Tofl er GH, Stone PH. Circadian variation and triggers of onset of acute cardiovascular disease. Circulation 1989; 79: 733-43.
2. Krieger J. Clinical presentations of sleep apnoea. European Respiratory Monograph 1998; 10: 75-105.
3. American Academy of Sleep Medicine Task Force. Sleeprelated breathing disorders in adults: recommendations for syndrome defi nition and measurement techniques in clinical research. Sleep 1999; 22: 667-89.
4. Kemmer H, Mathes AM, Dilk O, Gröschel A, Grass C, Stöckle M. Obstructive sleep apnea syndrome is associated with overactive bladder and urgency incontinence in men. Sleep 2009; 32: 271-5.
5. Moriyama Y, Miwa K, Tanaka H, Fujihiro S, Nishino Y, Deguchi T. Nocturia in men less than 50 years of age may be associated with obstructive sleep apnea syndrome. Urology 2008; 71: 1096-8.
6. Kemmer H. Th e relationship between sleep apnea and overactive bladder. Curr Urol Rep 2009; 10: 448-50.
7. Kemmer H. [Sleep apnea in urology. Infl uence of obstructive sleep apnea on erection and bladder function]. Urologe A 2009; 48: 1199-202 (article in German).
8. Oztura I, Kaynak D, Kaynak HC. Nocturia in sleep-disordered breathing. Sleep Med 2006; 7: 362-7.
9. Chartier-Kastler E, Leger D, Montauban V, Comet D, Haab F. [Impact of nocturia on sleep effi ciency in patients with benign prostatic hypertrophy]. Prog Urol 2009; 19: 333-40 (article in French).
10. Margel D, Shochat T, Getzler O, Livne PM, Pillar G. Continuous positive airway pressure reduces nocturia in patients with obstructive sleep apnea. Urology 2006; 67: 974-7.
11. Guilleminault C, Lin CM, Gonçalves MA, Ramos E. A prospective study of nocturia and the quality of life of elderly patients with obstructive sleep apnea or sleep onset insomnia. J Psychosom Res 2004; 56: 511-5.
12. Hajdug IA, Strollo PJ Jr, Jasani RR. Prevalence and predictors of nocturia in obstructive sleep apnea-hypopnea syndrome - a retrospective study. Sleep 2003; 26: 61-4.