Seçkin atletlerde tam kan viskozitesi ve sol ventrikül geometrisi: atlet kalbi üzerine bir çalışma

Amaç: Bu çalışmada, bir grup seçkin sporcudaki tam kan viskozitesi ile sol ventriküler yeniden şekillenme arasında olası ilişki değerlendirilmiştir.Gereç ve Yöntemler: Bu çalışma seçkin atletlerin (65 futbolcu, 12 basketbolcu) katılımı ile gerçekleştirildi. Sol ventrikül kütlesi, transtorasik ekokardiyografi ile hesaplandı. Tam kan viskozitesinin hesaplanması hematokriti ve toplam plazma protein konsantrasyonunu kullanan formüller aracılığıyla hem yüksek kesme hızı (HSR= 208/s) hem de düşük kesme hızında (LSR= 0.5/s) gerçekleştirildi. Sol ventrikül kütle indeksi 115 g/m2 üzeri olması sol ventrikül hipertrofisi olarak tanımlandı, Katılımcıların tam kan viskoziteleri ve klinik özellikleri sol ventrikül hipertrofisi olup olmamasına göre karşılaştırıldı. Bulgular: Çalışmaya katılan 24 sporcuda sol ventrikül hipertrofisi mevcut idi. Tam kan viskozitesi hem yüksek kesme hızında (sol ventrikül hipertrofisi olmayan grup için HSR tam kan viskozitesi=17,4±0,89 cP karşın hipertrofi olan grup HSR tam kan viskozitesi= 17,95±0,78 cP; p= 0,011), hem de düşük kesme hızında (sol ventrikül hipertrofisi olmayan grup için HSR tam kan viskozitesi=63,7±18,9 cP karşın hipertrofi olan grup LSR tam kan viskozitesi= 76,36±16,35 cP; p=0,006) sol ventrikül hipertrofisi olan sporcu grubunda anlamlı şekilde daha yüksekti. Çoklu değişkenli lojistik regresyon analizinde tam kan viskozitesi düşük ve yüksek kesme değerleri için ayrı ayrı ayrı modellere alındı. Tam kan viskozitesi hem düşük kesme hızında (OR=1,057, %95 CI: 1,017-1,098; p=0,005), hem de yüksek kesme hızında (OR=2,885, %95 CI: 1,319-6,313; p=0,008) sol ventrikül hipertrofisi ile ilişki bulundu. Sonuç: Seçkin sporcularda gözlenen sol ventrikül hipertrofisinde tam kan viskozitesinin muhtemel bir rolü olabilir.

Anahtar Kelimeler:

sporcu, sol ventrikül hipertrofisi, kan viskozitesi

Whole blood viscosity and left ventricle geometry in elite athletes: a study on athlete's heart

Aim: In this study, the relationship between whole blood viscosity and left ventricular remodeling in a group of elite athletes was evaluated.Material and Methods: This study was carried out with the participation of elite athletes (65 footballers, 12 basketball players). Left ventricular mass was calculated by transthoracic echocardiography. The calculation of the whole blood viscosity was performed by using both the high shear rate (HSR = 208/s) and the lower shear rate (LSR = 0.5/s) through the formulas using hematocrit and total plasma protein concentration. Left ventricular mass index above 115 g/m2 was defined as left ventricular hypertrophy. The whole blood viscosities and clinical features of the participants were compared according to the presence of left ventricular hypertrophy.Results: Left ventricular hypertrophy was present in 24 athletes.Left ventricular hypertrophy was present in 24 athletes. Whole blood viscosity at both high shear rate (HSR whole blood viscosity for the group without left ventricular hypertrophy = 17.4 ± 0.89 cP, vs HSR whole blood viscosity for the group with hypertrophy= 17.95 ± 0.78 cP; p = 0.011), LSR whole blood viscosity for group without left ventricular hypertrophy = 63.7 ± 18.9 cP vs LSR whole blood viscosity for the group with hypertrophy = 76.36 ± 16.35 cP; p = 0.006) left ventricular hypertrophy was significantly higher in the group of athletes. In multivariate logistic regression analysis, whole blood viscosity was taken to separate models for low and high shear rates. Whole blood viscosity at the low shear rate (OR=1.057, 95% CI: 1.017-1.098; p=0.005), as well as at the high shear rate (OR=2.885, 95% CI: 1.319-6.313; p=0.008) was significantly associated with left ventricular hypertrophy. Conclusion: Whole blood viscosity may have a possible role in left ventricular hypertrophy observed in elite athletes.

Keywords:

athlete, left ventricular hypertrophy, blood viscosity,

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