Kesitsel bir araştırma: Kolesterol oranlarının akut iskemik inme şiddeti üzerine etkisi var mı?

Amaç:İnme ve inme ile ilgili komplikasyonların önlenmesinin amacı, değiştirilebilir risk faktörlerini kontrol etmek ve ortadan kaldırmaktır. Hiperkolesterolemi bu risk faktörlerinden biri olduğundan, düşük dansiteli lipoprotein kolesterol (LDL-C) / yüksek dansiteli lipoprotein kolesterol (HDL-C) ve total kolesterol / HDL-C oranları ile NIHSS puanlarını karşılaştırarak, bu oranların inme ciddiyetine etkilerini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Bu retrospektif kesitsel araştırma iskemik inmeli 207 hastayı içermektedir. Hastaların demografik özellikleri, total kolesterol, trigliserit, herhangi bir lipid düşürücü ilaç kullanmayan hastaların LDL-C ve HDL-C düzeyleri ve NIHSS skorları bir veri toplama formunda kaydedildi. LDL-C / HDL-C ve total kolesterol / HDL-C oranlarının NIHSS puanlarına etkisi araştırıldı. Bulgular:Hastaların yaş ortalaması 69.3 idi. Tüm bu hastalar arasında ortalama LDL-C / HDL-C oranı 2.93 ve total kolesterol / HDL-C oranı 4.68 idi. Başvuru sırasında NIHSS'nin ortalama puanı 7.05 idi. Tüm bu parametreler arasında istatistiksel olarak anlamlı bir fark veya korelasyon gözlenmedi.Sonuç:Başvuru sırasında HDL-C / LDL-C ile total kolesterol / HDL-C oranları ve NIHSS skorları arasında istatistiksel olarak anlamlı bir ilişki gözlenmedi. İskemik inme risklerini göz önünde bulundurarak uygun parametreleri bulmak için ileriye dönük çok merkezli çalışmalara ihtiyaç vardır.

Anahtar Kelimeler:

iskemik inme, HDL-C, LDL-C

A cross‐sectional study: Is there any effects of cholesterol ratios on acute ischemic stroke severity?

Aim: The aim of prevention of stroke and stroke related complications is to control and eliminate modifiable risk factors. Since hypercholesterolemia is one of these risk factors, we aimed to compare the low density lipoprotein cholesterol (LDL-C) / high density lipoprotein cholesterol (HDL-C) and total cholesterol / HDL-C ratios with NIHSS scores and to evaluate the effects of these ratios on the severity of stroke.Material and Methods:This retrospective cross-sectional study included 207 patients with ischemic stroke. Demographic characteristics, total cholesterol, triglycerides, LDL-C and HDL-C levels of patients who did not use any lipid-lowering drug and NIHSS scores were recorded in a data collection form.The effects of LDL-C / HDL-C and total cholesterol / HDL-C ratios on NIHSS scores were investigated.Results:The mean age of the patients was 69.3 years. The mean LDL-C / HDL-C ratio was 2.93 and the total cholesterol / HDL-C ratio was 4.68. The mean score of NIHSS was 7.05 at admission. No statistically significant difference or correlation was observed between all these parameters. Conclusion:There was no statistically significant relationship between HDL-C / LDL-C and total cholesterol / HDL-C ratios and NIHSS scores. Considering the risk of ischemic stroke, prospective multicentric studies are needed to find proper parameters.

Keywords:

ischemic stroke, HDL-C, LDL-C,

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