Yaşar DÜRÜST, Eda SAĞIRLI, Akin SAĞIRLI

7893

Microwave-assisted regioselective [1,3]-dipolar cycloaddition of 3-methyl-2-(substitutedbenzylidene)-5-oxopyrazolidin-2-ium-1-ides to benzothiophene 1,1-dioxide

A series of pyrazolidinium ylides was reacted with benzothiophene 1,1-dioxide to afford (3R,5S,5aS,10bS)-3-methyl-5-substitutedphenyl-2,3,5,5a-tetrahydrobenzo[4,5]thieno[3,2-c]pyrazolo[1,2-a]pyrazol-1(10bH)-one 6,6-dioxides under microwave irradiation and their structures were identified by means of spectral/physical characteristics including X-ray diffraction data and HRMS measurements.
Anahtar Kelimeler:

Microwave-assisted synthesis, pyrazolidinium, ylide, 1, 3-dipolar cycloaddition, benzothiophene dioxide

Microwave-assisted regioselective [1,3]-dipolar cycloaddition of 3-methyl-2-(substitutedbenzylidene)-5-oxopyrazolidin-2-ium-1-ides to benzothiophene 1,1-dioxide

A series of pyrazolidinium ylides was reacted with benzothiophene 1,1-dioxide to afford (3R,5S,5aS,10bS)-3-methyl-5-substitutedphenyl-2,3,5,5a-tetrahydrobenzo[4,5]thieno[3,2-c]pyrazolo[1,2-a]pyrazol-1(10bH)-one 6,6-dioxides under microwave irradiation and their structures were identified by means of spectral/physical characteristics including X-ray diffraction data and HRMS measurements.
Keywords:

Microwave-assisted synthesis, pyrazolidinium, ylide, 1, 3-dipolar cycloaddition, benzothiophene dioxide,

PDF

___

  • (1S,4aR,9bR,10S )-10-(4-(Dimethylamino)phenyl)-1-methyl-1,2,9b,10-tetrahydrobenzo [4,5]thieno[2,3-c]pyrazolo[1,2-a]pyrazol-3(4aH)-one 5,5-dioxide 5l White solid, yield: 70 mg, 71%: mp 205–207 ◦ C; Rf: 0.20 (EtOAc: n -hexane, 1:1). IR (KBr, cm 2928, 1685 (C=O), 1612, 1523, 1408, 1311 (SO2asym), 1192 (SO sym), 910, 825, 732.1H NMR (400 MHz,
Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Arşiv
Sayıdaki Diğer Makaleler

Purification, refolding, and characterization of recombinant human paraoxonase-1

Yeliz DEMİR, Şükrü BEYDEMİR

Synthesis of 5-aryl-$N$-(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide via three-component reaction of trichloroacetyl isocyanate, ($N$-isocyanimino)triphenylphosphorane, and benzoic acid derivatives

NAHID SHAJARI, ALI REZA KAZEMIZADEH, ALI RAMAZANI

Simultaneous analysis of losartan, its active metabolite, and hydrochlorothiazide in human plasma by a UPLC-MS/MS method

Priyanka A. SHAH, Primal SHARMA, Jaivik V. SHAH, Mallika SANYAL, Pranav S. SHRIVASTAV

Functional gold nanoparticle coated surfaces for CA 125 cancer biomarker detection

İlknur TUNÇ, Hepi Hari SUSAPTO, Mustafa Özgür GÜLER

Synthesis and characterization of novel urea and thiourea substitute cyclotriphosphazene compounds as naked-eye sensors for F$^{-}$ and CN$^{-}$ anions

Hava ÖZAY, Mehmet YILDIRIM, Özgür ÖZAY

Microwave-assisted regioselective [1,3]-dipolar cycloaddition of 3-methyl-2-(substitutedbenzylidene)-5-oxopyrazolidin-2-ium-1-ides to benzothiophene 1,1-dioxide

Yaşar DÜRÜST, Eda SAĞIRLI, Akin SAĞIRLI

Conversion of racemic allylic hydroperoxides into corresponding chiral 1/2,3-triols by using catalytic OsO$_{4}$ and chiral cinchona ligands in the absence of co-oxidant

Haydar GÖKSU, Mehmet Serdar GÜLTEKİN

A comparative study on fabrication of Cu2ZnSnS4 (CZTS) nanofibers using acetate and chloride metal precursors

Mahmut KUŞ, Halit ÇAVUŞOĞLU, Faruk ÖZEL, Mustafa ERSÖZ, Burak Zafer BÜYÜKBEKAR, Hüseyin ŞAKALAK, Mustafa Selman YAVUZ

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-a]pyridine derivatives

Ming-Yan YANG, Lin-Jiong ZHANG, Zhao-Hui SUN, Xing-Hai LIU, Jian-Quan WENG, Cheng-Xia TAN, Bei-Zhen HU

A case study on in vitro investigations of the potent biological activities of wheat germ and black cumin seed oil

Didem Ağ ŞELECİ, Zinar Pinar GÜMÜŞ, Murat YAVUZ, Muharrem ŞELECİ, Rebecca BONGARTZ, Frank STAHL, Hakan COŞKUNOL, Suna TİMUR, Thomas SCHEPER