Facile synthesis of 5-bromotropono[c]-fused pyrazoles and isoxazole

A facile synthesis of a series of new 5-bromotropono[c]pyrazole derivatives (3 and 10--15) as well as 5-bromotropono[c]isoxazole (17) is described, involving a condensation reaction of 3-acetyl-5-bromotropolone (1) with hydrazine monohydrate (2), arylhydrazine hydrochlorides (4--9), and hydroxylamine hydrochloride (16), respectively. All the synthesized compounds were obtained in good yields of 56%--77% and their structures were characterized by spectral data and HRMS.

Anahtar Kelimeler:

Tropono[c]pyrazole, tropono[c]isoxazole, condensation reaction, hydrazine monohydrate, arylhydrazine, hydroxylamine

Facile synthesis of 5-bromotropono[c]-fused pyrazoles and isoxazole

Keywords:

Tropono[c]pyrazole, tropono[c]isoxazole, condensation reaction, hydrazine monohydrate, arylhydrazine, hydroxylamine,

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