Ergenlikte Kawasaki hastalığı

Kawasaki hastalığı, erken çocukluk döneminde görülen, koroner arter tutulumu nedeniyle hastalık ve ölüme yol açan bir vaskülittir. Büyük çocuk ve ergenlerde nadir görülmesi tanının gecikmesine neden olarak koroner arter tutulumu için bir risk etmeni oluşturabilir. Kliniğimizde ergen yaşta Kawasaki hastalığı tanısı koyduğumuz koroner arter genişlemesi ve akciğer tutulumu da gözlenen bir olgumuzu sunuyoruz.

Kawasaki disease in adolescence

Kawasaki disease is a vasculitis causing morbidity and mortality due to coronary artery involvement which is more frequent during infancy and early childhood. Since the disease is rare in older children and adolescents, the diagnosis may be delayed and the risk of coronary artery involvement may increase. We herein present a case of Kawasaki disease diagnosed in an adolescent patient, involving the coronary arteries and the lungs.

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1. Newbuger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 2004; 110(17): 2747-71.
2. Masato T, Newburger JW. Kawasaki syndrome (mucocutaeous lymph node syndrome). Moss and Adam’s heart disease in infants, children, and adolescents. 7th edition. Philadelphia: Lippincott Williams & Wilkins (LWW) 2008; 61: 1242-56.
3. Hara T, Mizuno Y, Akeda H, et al. Thrombocytopenia: a complication of Kawasaki disease. Eur J Pediatr 1988; 147(1): 51-3.
4. Stockheim JA, Innocentini N, Shulman ST. Kawasaki disease in older children and adolescents. J Pediatr 2000; 137(2): 250-2.
5. Sève P Stankovic K, Smail A, Durand DV, Marchand G, Broussolle C. Adult Kawasaki disease: report of two cases and literature review. Semin Arthritis Rheum 2005; 34(6): 785-92.
6. Uziel Y, Hashkes PJ, Kassem E, Gottesman G, Wolach B. ‘Unresolving pneumonia” as the main manifestation of atypical Kawasaki disease. Arch Dis Child 2003; 88(10): 940-2.
7. Sengler C, Gaedicke G, Wahn U, Keitzer R. Pulmonary symptoms in Kawasaki disease. Pediatr Infect Dis J 2004; 23(8): 782-4.
8. Hyun JK, Soo JL. Two cases of Kawasaki disease following pneumonia. Korean J Pediatr 2009; 52(5): 615-8.
9. Umezawa T, Saji T, Matsuo N, Odagiri K. Cheest X-ray findings in the acute phase of Kawasaki disease. Pediatr Radiol 1989; 20(1-2): 48-51.
10. Dajani AS, Taubert KA, Gerber MA, et al. Diagnosis and therapy of Kawasaki disease in children. Circulation 1993; 87(5): 1776-80.
11. Tsuda E, Kamiya T, Ono Y, Kimura K, Kurosaki K, Echigo S. Incidence of stenotic lesions predicted by acute phase changes in coronary arterial diameter during Kawasaki disease. Pediatr Cardiol 2005; 26(1): 73-9.
12. Tsuda E, Kamiya T, Ono Y, Kimura K, Echigo S. Dilated coronary arterial lesions in the late period after Kawasaki disease. Heart 2005; 91(2): 177-82.
13. Kato H, Sugimura T, Akagi T, et al. Long-term consequences of Kawasaki disease. A 10- to 21-year follow-up study of 594 patients. Circulation 1996; 94(6): 1379-85.