Meryem EKEN, Doğukan ARIĞIN, Ecmel KAYGUSUZ, Mesut POLAT, Ateş KARATEKE

SERTOLİ LEYDİG HÜCRELİ TÜMÖR: 4 OLGU SUNUMU VE LİTERATÜRÜN GÖZDEN GEÇİRİLMESİ

Sertoli-Leydig hücreli tümörler tüm over tümörlerinin %0.5’inden azını oluştururlar. Sertoli-Leydig hücreli tümör hastanemizde son 5 yıl içinde 4 olguda gözlendi. Olguların yaşı 25 ile 73 arasında değişmekte idi ve ortalama yaş 43 idi. Bir hasta sekonder amenore ve virilizasyon, dört hastanın üçü ise kasık ağrısı ile başvurdu. İki hastaya total abdominal histerektomi ve bilateral salfingoooferektomi, iki hastaya unilateral salfingoooferektomi uygulandı. Takiplerde rekürrens/metastaz saptanmadı. Bu olgular klinikopatolojik bulguları literatür eşliğinde gözden geçirilmiştir.

Anahtar Kelimeler:

Sertoli Leydig Hücreli Tümör, Over, Virilizasyon.

SERTOLI LEYDIG CELL TUMOR: REPORT OF 4 CASES AND REVIEW OF THE LITERATURE

Sertoli-Leydig cell tumors constitude 0.5% of all ovarian tumors. Sertoli-Leydig cell tumor has been diagnosed in four patients in the last 5 years period in our hospital. The ages ranged from 25 to 73 years, with a mean of 43 years. One patient presented with secondary amenorrhea and virilization, three of the four patients showing groin pain. Histologically, four tumors were intermediated differentiated. Two patients underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy and two were treated by unilateral salpingo-oophorectomy. Recurrence/metastasis was not noted in all cases with follow-up data. The clinicopathologic features of these cases are described and the relevant literature is reviewed

Keywords:

Sertoli-Leydig cell tumor, Ovary, Virilization,

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