Halil EKİNCİ, Turan BUZGAN, Banu EKİNCİ, Fatih KARA, Bekir KESKİNKILIÇ, Hasan IRMAK

Kronik hastalığı olan erişkinlerin 2015-2017 yılları arasında influenzaya karşı aşılanma durumları

Amaç: Türkiye’de kronik hastalığı olanlarda cinsiyet ve yaş grubu faktörleri de göz önünde bulundurularak influenza aşısı yapılma oranlarının araştırılması amaçlanmıştır. Yöntem: 2011 yılında Türkiye Kronik Hastalıklar ve Risk Faktörleri Çalışması için verileri toplanan 18477 kişinin, elektronik sağlık kayıtlarından hastalık bilgileri alınmıştır. Erişkin aşılamasında önerilen tüm aşılar arasında, 2015-2017 yılları arasında yeterli verisi bulunan kişilerin; sosyodemografik özellikler, kronik hastalık varlığı, yaş ve cinsiyete göre influenza aşılanma oranları incelenmiştir. Bulgular: Cinsiyete göre erkeklerde influenza aşılanma oranı (yüzbinde 391) ile kadınların aşılanma oranı (yüzbinde 367) arasında anlamlı bir fark saptanmamıştır. (?2 = 0,729, ?? = 1, p=0,207). Yaş grubuna göre (45-54, 55-64, 65-74 ve 75+ yaş grupları arasında) aşılanma oranları anlamlı fark göstermiştir. (?2 = 183,012, ?? = 3, p

Influenza vaccination status in adults with chronic diseases between 2015-2017

Objective: In Turkey, it was aimed to investigate the rate of influenza vaccination in patients with chronic diseases, taking into account the factors of gender and age group. Methods: Disease information was obtained from the electronic health records of 18477 people whose data were collected for the Turkey Chronic Diseases and Risk Factors Study in 2011. Among all vaccines recommended in adult vaccination, for influenza vaccine with sufficient data in 2015-2017; Influenza vaccination rates according to sociodemographic characteristics, presence of chronic diseases, age and gender were examined. Results: There was no significant difference between the influenza vaccination rate in men (391 per hundred thousand) and the vaccination rate of women (367 per hundred thousand) according to gender. (?2 = 0,729, ?? = 1, p=0,207). Vaccination rates by (in between 45-54, 55- 64, 65-74 ve 75+) age group showed a significant difference (?2 = 183,012, ?? = 3, p

PDF

___

1. AR Omran. The epidemiologic transition: a theory of the epidemiology of population change. Milbank Q, 2005; 83(4): 731–57.
2. RE McKeown. The epidemiologic transition: changing patterns of mortality and population dynamics. Am J Lifestyle Med, 2009; 3(1 Suppl): 19S-26S.
3. Türkiye Kalp ve Damar Hastaliklarini Önleme ve Kontrol Programi Birincil, İkincil ve Üçüncül Korumaya Yönelik Stratejik Plan ve Eylem Planı. Ankara: T.C. Sağlık Bakanlığı. 2010.
4. People at High Risk For Flu Complications. https://www.cdc.gov/flu/highrisk/index.htm, Erişim Tarihi: 10 Mart 2021.
5. Evaluation of influenza vaccine effectiveness: a guide to the design and interpretation of observational studies. Geneva: World Health Organization. 2017. https://apps.who.int/iris/ handle/10665/255203, Erişim Tarihi: 25 Mart 2021.
6. Lozano R, Naghavi M, Foreman K,Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 2012; 380 (9859): 2095-128.
7. Nair H, Brooks WA, Katz M,Roca A, Berkley JA, Madhi AS, Simmerman JM, et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta- analysis. Lancet, 2011; 378(9807): 1917-30.
8. Erişkin Bağışıklama Rehberi. https://www. ekmud.org.tr/haber/264-turkiye-ekmud-eriskin- bagisiklama-rehberi, Erişim Tarihi: 25 Mart 2021.
9. Seyahat Sağlığı 2021. https://www.seyahatsagligi. gov.tr/site/HastalikDetay/Grip, Erişim Tarihi: 10 Mart 2021.
10. Background paper on inflüenza vaccine and immunization. 2013, 1–48. http://www.who. int/immunization/sage/meetings/2012/april/1_ Background_Paper_Mar26_v13_cleaned.pdf?ua=1, Erişim Tarihi: 10 Mart 2021.
11. Grohskopf LA, Alyanak E, Broder KR, Blanton LH, Fry MA, Jernigan DB, et al., Prevention and control of seasonal inflüenza with vaccines: recommendations of the advisory committee on immunization practices-United States, 2020-21 influenza season MMWR Recomm Reports, 2020; 69 (8):1-24.
12. Key Facts About Seasonal Flu Vaccine. https://www.cdc.gov/flu/prevent/keyfacts. htm#benefits, Erişim Tarihi: 10 Mart 2021.
13. Kwong JC, Schwartz KL, Campitelli MA, Chung H, Crowcroft NS, Karnauchow T, et al. Acute myocardial infarction after laboratory-confirmed influenza infection. N Engl J Med, 2018; 378: 345- 53.
14. Seasonal influenza vaccines: an overview for decision-makers. https://apps.who.int/iris/ handle/10665/336951, Erişim Tarihi: 20 Mart 2021.
15. MacIntyre CR et al., Ischaemic heart disease, influenza and influenza vaccination: a prospective case control study. Heart; 100(6): 517–8.
16. Siriwardena AN, Gwini SM, Coupland CAC. İnfluenza vaccination, pneumococcal vaccination and risk of acute myocardial infarction: Matched case - control study. Cmaj, 2010; 182 (15): 1617– 23.
17. Hsu SY, Chen FL, Liaw YP, Huang JY, Nfor ON, Chao DY. A matched influenza vaccine strain was effective in reducing the risk of acute myocardial infarction in elderly persons: a population-based study. Medicine, 2016; 95 (10): 1–6.
18. Udell JA, Zawi R, Bhatt DL, Keshtkar-Jahromi M, Gaughran F, Ciszewski A. Association between influenza vaccination and cardiovascular outcomes in high-risk patients: a meta-analysis, JAMA, 2013; 23, 310 (16): 1711-20.
19. Lu PJ, Hung MC, Srivastav A, Grohskopf La, Kobayashi M, Harris AM, et al. Surveillance of vaccination coverage among adult populations - United States, 2018. MMWR Surveill Summ, 2021; 70(3): 1–26.
20. Fan J, Cong S, Wang N, Bao H, Wang B, Feng Y, et al. Influenza vaccination rate and its association with chronic diseases in China: results of a national cross-sectional study. Vaccine, 2020;38(11):2503- 11.
21. Nitsch-Osuch A, Gołębiak I, Wyszkowska D, Rosińska R, Kargul L, Szuba B, et al. Influenza vaccination coverage among polish patients with chronic diseases. Adv Exp Med Biol, 2017; 968:19- 34.
22. Rizzo C, Rezza G, Ricciardi W. Strategies in recommending influenza vaccination in Europe and US. Hum Vaccin Immunother, 2018;;14(3):693- 8.
23. Gross PA, Hermogenes AW, Sacks HS, Lau J, Levandowski RA. The efficacy of influenza vaccine in elderly persons. a meta-analysis and review of the literature. Ann Intern Med, 1995;123(7):518- 27.
24. Mouratidou E,Lambrou A, Andreopoulou A, Gioula G, Exindari M, Kossyvakis A, et al. Influenza vaccine effectiveness against hospitalization with laboratory-confirmed influenza in Greece: a pooled analysis across six seasons, 2013–2014 to 2018–2019. Vaccine, 2020; 38 (12): 2715–24.
25. Wang CS, Wang ST, Chou P. Efficacy and cost- effectiveness of influenza vaccination of the elderly in a densely populated and unvaccinated community. Vaccine,2002; 20 (19–20): 2494-9.
26. Kopsaftis Z, Wood-Baker R, Poole P. Influenza vaccine for chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev. . 2018; 6(6): CD002733.
27. Vasileiou E, Sheikh A, Butler C, Ferkh KE, von Wissmann B, McMenamin J, et al. Effectiveness of influenza vaccines in asthma: a systematic review and meta-analysis . Clin Infect Dise, 2017, 65(8): 1388-95.
28. Christiansen CF, Thomsen RW, Schmidt M et al. Influenza vaccination and 1-year risk of myocardial infarction, stroke, heart failure, pneumonia, and mortality among intensive care unit survivors aged 65 years or older: a nationwide population-based cohort study. Intensive Care Med 45, 2019; 45: 957–67.
29. Sung LC, Chen CI, Fang YA, Lai CH, Hsu YP , Cheng TH, et al. Influenza vaccination reduces hospitalization for acute coronary syndrome in elderly patients with chronic obstructive pulmonary disease: a population-based cohort study. Vaccine, 2014; 32 (30): 3843-9.
30. Rivetti D, Jefferson T, Thomas R, Rudin M, Rivetti A, Pietrantonj C Di, et al. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev, 2006;(3):CD004876.
31. Hekimoğlu CH, Emek M, Avcı E, Topal S, Demiröz M, Ergör G. Seasonal influenza vaccine effectiveness in preventing laboratory confirmed influenza in 2014-2015 season in Turkey: a test-negative case control study. Balkan Med J, 2018;35:77-83.
32. Liprandi ÁS , Liprandi MIS , Zaidel EJ, Aisenberg GM, Baranchuk A, bir yazar daha eklenecek, et al. Influenza vaccination for the prevention of cardiovascular disease in the americas: consensus document of the Inter-American society of cardiology and the world heart federation. Glob Heart, 2021;16(1):55.
33. Fica CA, Antunez RM, Cuevas AK, Rodriguez NA, Aravena RP. Prescripción de la vacuna anti influenza por médicos institucionales y estudiantes de especialidades médicas en un hospital docente. Rev Chil Infectol, 2001; 18(1): 20-27.
34. Hershey CO, Karuza J. Delivery of vaccines to adults: correlations with physician knowledge and patient variables. Am J Med Qual, 1997; 12(3): 143–50.
35. Olasupo OO, Brown J, Segal R. Missed opportunities for influenza and pneumococcal vaccinations in the elderly in the US – A cross-sectional analysis. Value Health, 2018; 21: S158.
36. Davis BM, Black D. Identifying the challenges to adult influenza vaccination in Latin America. Value Health, 2017; 20(9): A934.
37. Zimmerman RK, Santibanez TA, Janosky JE, Fine MJ, Raymund M, Wilson SA, et al. What affects influenza vaccination rates among older patients? an analysis from inner-city, suburban, rural, and Veterans Affairs practices. Am J Med, 2003; 114(1): 31–8.
38. Bovier PA, Chamot E, Bouvier Gallacchi M, Loutan L. Importance of patients’ perceptions and general practitioners’ recommendations in understanding missed opportunities for immunisations in Swiss adults. Vaccine, 2001; 19(32): 4760–7.
39. Srivanichakom W, Asavathitanonta K, Washirasaksiri C, Chaisathaphon T, Chouriyagune C, Phisalprapa P, et al. Prescribing rate of influenza vaccine among internal medicine residents for outpatient continuum care. J Med Assoc Thail Chotmaihet Thangphaet, 2014; 97(12): 1281–9.
40. Jaiyeoba O, Villers M, Soper DE, Korte J, Salgado CD. Association between health care workers’ knowledge of influenza vaccine and vaccine uptake. Am J Infect Control, 2014; 42(1): 69–70.
41. Larson HJ, de Figueiredo A, Xiahong Z, Schulz WS, Verger P, Johnston IG, et al. The state of vaccine confidence 2016: global insights through a 67-country survey. EBioMedicine. 2016; 12: 295– 301.
42. Bertoldo G, Pesce A, Pepe A, Pelullo CP, Di Giuseppe G. Collaborative Working Group. Seasonal influenza: Knowledge, attitude and vaccine uptake among adults with chronic conditions in Italy. PLoS One, 2019; 14(5): e0215978.
43. Schmid P, Rauber D, Betsch C, Lidolt G, Denker M-L. Barriers of influenza vaccination intention and behavior – a systematic review of influenza vaccine jesitancy, 2005 – 2016. PLoS One. 2017; 12(1): e0170550.
44. Aile Hekimliği Uygulama Yönetmeliği, Ankara: T.C. Sağlık Bakanlığı. 2013.
45. Bora Başara B, Soytutan Çağlar İ, Aygün A ve ark. Ankara: Sağlık Bilgi Sistemleri Genel Müdürlüğü. https://sbsgm. saglik.gov.tr/Eklenti/40564/0/ saglik-istatistikleri-yilligi-2019pdf.pdf., Erişim Tarihi: 10 Mart 2021.