Fevzi TORAMAN, Şahin ŞENAY, Ahmet AKYOL, Hasan KARABULUT, Sinan DAĞDELEN

Yüksek riskli aort darlığı olan hastalarda transkateter aortik kapak implantasyonu: Klinik takip

Amaç: Çalışmamızda transkateter aortik kapak implantasyonu (TAVI) uygulanan hastalarda erken ve orta dönem sonuçları değerlendirildi. Çalışma planı: Ocak 2010 - Nisan 2011 tarihleri arasında kliniğimizde c iddi a ort d arlığı n edeni i le TAVI uygulanan v e cerrahi riski yüksek olan 10 hastanın (7 kadın, 3 erkek; ort. yaş 80.4±6.7 yıl; dağılım 64-88 yıl) erken ve orta dönem sonuçları değerlendirildi. Tüm hastalara transfemoral yaklaşım ile Edwards Sapien biyoprotez kapak yerleştirildi ve 6.1±5.2 ay takip edildi. Bulgular: İşlem öncesi ortalama fonksiyonel sınıf NYHA 3.8±0.4, ortalama aortik kapak alanı (AKA) 0.6±0.1 cm2, ortalama sol ventrikül ejeksiyon fraksiyonu (sol VEF) %55.4±9.8 ve maksimal (MAG) ve ortalama aortik kapak gradiyentleri (OAG) sırasıyla 94.3±24.2 ve 54.5±17.7 mmHg idi. Bu aşamada herhangi bir ek girişimsel işlem gerekmedi. Teknik başarı oranı %100 idi ve her hastaya tek bir kapak yerleştirildi. Takip süresinde ne mortalite ne de majör inme görüldü. TAVİ işlemini takiben NYHA 1.9±0.6’ya düştü (p

Transcatheter aortic valve implantation in patients with high-risk aortic stenosis: a clinical follow-up

Background: This study aims to evaluate early- and mid-term results of our patients who underwent transluminal aortic valve implantation (TAVI). Methods: The early- and mid-term results of 10 patients (7 females, 3 males; mean age 80.4±6.7 years; range 64 to 88 years) with high surgical risk who underwent the TAVI procedure in our clinic between January 2010 and April 2011 were evaluated. All of our patients were implanted with Edwards Sapien bioprosthetic valves through the transfemoral approach and followed-up for 6.1±5.2 months. Results: Before the procedure, the mean functional class was NYHA 3.8±0.4, the mean aortic valve area (AVA) was 0.6±0.1cm2, the left ventricular ejection fraction (LVEF) was %55.4±9.8 and the mean peak (PAG) and mean valvular gradients (MAG) were 94.3±24.2 and 54.5±17.7 mmHg, respectively. No additional interventional procedure was required during this stage. The technical success rate was 100%, and a single valve was implanted in all patients. Neither mortality nor major strokes were observed during the follow-up period. Following the TAVI procedure, the NYHA decreased to 1.9±0.6 (p

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