Mehmet Oğuzhan ÖZYURTKAN, Mustafa AKIN

Primary pleural leiomyosarcoma presenting as multiple pleural masses

Bu makalede, üç plevral kitle ile kendini gösteren primerplevral leiomyosarkomlu 74 yaşında bir kadın hastasunuldu. İki diyafragmatik kitle torakoskopi ile tamameneksize edildi. Pozitron emisyon tomografisinde primerköken alanın apikal kitle olduğu görüldü; bu kitle aksillertorakotomi ile tamamen eksize edildi. Cerrahi sınırlarnegatif olduğundan, hastaya ameliyat sonrası kemo- veyaradyoterapi verilmedi ve hasta 17 aylık takip sonucundahastalıksız durumdadır. Cerrahi rezeksiyon leiomyosarkomtedavisinin temelini oluşturur. Metastatik olmayanolgularda veya cerrahi sınırlar negatif olduğunda, ameliyatsonrası kemo- veya radyoterapi gerekli olmayabilir.Bilgimiz dahilinde, literatürde multipl plevral kitlelerşeklinde kendini gösteren primer plevral leiomyosarkomolgusu bildirilmemiştir.

Multipl plevral kitleler şeklinde kendini gösteren primer plevral leiomyosarkom

In this article, we report a 74-year-old female patientwith primary pleural leiomyosarcoma presenting withthree pleural masses. Two diaphragmatic masses werecompletely excised via thoracoscopy. A positron emissiontomography showed the apical mass as the primary siteof origin, which was completely excised via axillarythoracotomy. As surgical margins were negative, patientwas not given chemo- or radiotherapy, and is disease- free after 17 months of follow-up. Surgical resectionis the mainstay of treatment of leiomyosarcoma. Innonmetastatic cases or when the surgical margins arenegative, postoperative chemo- or radiotherapy maynot be required. To our knowledge, there is no case ofprimary pleural leiomyosarcoma presenting with multiplepleural masses reported in the literature.

PDF

___

1. Gladish GW, Sabloff BM, Munden RF, Truong MT, Erasmus JJ, Chasen MH. Primary thoracic sarcomas. Radiographics 2002;22:621-37.
2. Rais G, Raissouni S, Mouzount H, Aitelhaj M, Khoyaali S, El Omrani F, et al. Primary pleural leiomyosarcoma with rapid progression and fatal outcome: a case report. J Med Case Rep 2012;6:101.
3. Al-Daraji WI, Salman WD, Nakhuda Y, Zaman F, Eyden B. Primary smooth muscle tumor of the pleura: a clinicopathological case report with ultrastructural observations and a review of the literature. Ultrastruct Pathol 2005;29:389-98.
4. Knuuttila A, Jee KJ, Taskinen E, Wolff H, Knuutila S, Anttila S. Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases. Virchows Arch 2006;448:135-41.
5. Ouadnouni Y, Bouchikh M, Jahid A, Achir A, Msougar Y, Smahi M, et al. Primary pleural leiomyosarcoma: a case report. Louvain Med 2010;129:241-3.