Postoperative delirium associated with prolonged decline in cognitive function and sleep disturbances after cardiac surgery

Amaç: Bu çalışmada ameliyat sonrası deliryum ve kognitif disfonksiyon arasındaki ilişki ve ameliyat sonrası deliryumun kardiyak cerrahi sonrası uzun dönemdeki kognitif fonksiyon ve uyku bozuklukları üzerine olan etkileri araştırıldı. Çalışma planı: Mayıs 2010 - Temmuz 2011 tarihleri arasında kliniğimizde açık kalp ameliyatı geçiren 285 hastadan çalışma kriterlerine uyan toplam 51 ardışık hasta çalışmaya alındı. Çalışmada ameliyat sonrası deliryum tanısı konulan 26 hasta (grup 1), deliryum tanısı konulmayan 25 hasta (grup 2) ile karşılaştırıldı. Kognitif fonksiyon, hastane taburculuğu öncesinde ameliyat sonrası 6. ve 12. ayda standardize mini-mental durum muayenesi (MMSE) testi ile değerlendirildi. Her iki grubun ameliyat sonrası 12. ayda çalışma hayatına katılımları sorgulandı. Fonksiyonel becerileri enstrümental günlük yaşam aktiviteleri (EGYA) için yardım ihtiyacı ile değerlendirirken, uyku sorunları, Pittsburgh uyku kalite indeksi (PSQI) ile değerlendirildi.Bulgular: Grup 1’deki hastaların ortalama MMSE skorları, grup 2’deki hastalara kıyasla, taburculuk öncesinde daha düşüktü (26.0 ile 28.6, p

Kardiyak cerrahi sonrası uzayan kognitif fonksiyon kaybı ve uyku bozuklukları ile ilişkili ameliyat sonrası deliryum

Background: This study aims to investigate the association between postoperative delirium and cognitive dysfunction after cardiac surgery and to determine the effects of postoperative delirium on postoperative cognitive dysfunction and sleep disturbances in the long-term. Methods: Among 285 patients who underwent open cardiac surgery between May 2010 and July 2011, 51 patients who met the inclusion criteria were enrolled in the study. Twenty-six patients (group 1) who developed postoperative delirium were compared with 25 patients (group 2) without delirium. Cognitive function was assessed by mini-mental state examination (MMSE) test at pre-discharge, six and 12 months after surgery. Involving into the working life was questioned in both groups at the 12 months after surgery. Functional ability was assessed by the assistance need for instrumental activities of daily living (IADL), whereas sleep disturbances were assessed by the Pittsburgh sleep quality index (PSQI).Results: Patients in group 1 had lower mean MMSE scores compared to patients in group 2 before hospital discharge (26.0 versus 28.6, p

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