Hasan EKİM, Adem KIYMAZ, Elif ARI, Dolunay ODABAŞI

Hemodiyalize bağımlı son dönem böbrek yetmezliği hastalarında sekonder arteriyovenöz fistül oluşturmak için sentetik greft yerine safen ven greft kullanalım mı?

Amaç: Hemodiyaliz (HD) için eş zamanlı olarak safen ven (SV) greft ve politetrafloroetilen (PTFE) greft ile sekonder arteriyovenöz fistül (AVF) oluşturulmuş hasta grupları, açıklık ve komplikasyon oranları yönünden gözden geçirildi. Çalışma planı: Ocak 2006 ile Ocak 2010 tarihleri arasında ardışık 40 hastada 40 HD erişim işlemi uygulandı. Tüm erişim girişimleri kol ve önkolun venlerinde ameliyat öncesi dubleks ultrasonografi (USG) taramaları ile gerçekleştirildi. Fonksiyonel açıklık hastanın başarılı bir şekilde HD yapılabilmesi olarak tanımlandı. Safen ven ve PTFE greftlerin toplam primer ve sekonder fonksiyonel açıklıkları Kaplan Meier yöntemi ile açıklık oranları arasındaki farklar Log-Rank testi ile tomboliz, trombektomi ve ameliyata bağlı revizyonlar gibi revizyon oranları arasındaki farklar ise Z testi ve Fisher exact t-testi ile belirlendi. Bulgular: Ortalama takip süresi 48 ay (dağılım 43-54 ay) idi. Her iki grubun risk faktörleri benzer idi. Safen ven greft daha uzun süreli açıklık oranlarına sahip idi. Hemodiyaliz giriş komplikasyonları SV greft grubunda daha yüksek iken, enfeksiyon ve tromboz PTFE greft grubunda daha yüksek idi. Sonuç: Bizim verilerimiz üst ekstremitesinde sekonder AVF açılabilecek hastalarda, anatomik kriterlere bağlı olarak SV greftin PTFE greftten daha önce düşünülmesi gerektiğini kuvvetle desteklemektedir.

Should we use saphenous vein graft instead of synthetic graft for creation of secondary arteriovenous fistula in hemodialysis dependent end stage renal failure patients?

Background: Patient groups with secondary arteriovenous fistula (AVF) management with saphenous vein (SV) graft and polytetrafluoroethylene (PTFE) graft for hemodialysis (HD) were reviewed in terms of patency and complication rate. Methods: Forty HD access procedures were performed in 40 consecutive patients between January 2006 and January 2010. All access procedures were planned on the basis of preoperative duplex ultrasonography (USG) scans of arm and forearm veins. Functional patency was defined as ability to cannulate for HD successfully for the patient. Primary and secondary cumulative functional patency of SV and PTFE grafts were determined with Kaplan Meier test; differences in patency rates were analyzed with Log Rank test and differences in revision rates including thrombolysis, thrombectomies and operative revisions were analyzed with the Z test and the Fisher’s exact t-test. Results: Mean follow-up was 48 months (range 43-54 months). Risk factors were similar between the two groups. Saphenous vein graft had better patency rates. The HD access complications were higher in SV graft group, while infection and thrombosis were higher in PTFE group. Conclusion: Our data strongly support the necessity that SV graft should be considered initially, compared to PTFE graft, for the patient who is a candidate for an upper arm secondary AVF creation based on anatomical criteria.

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