Comparison of thoracic paravertebral and epidural blocks for pain relief after thoracotomy
Amaç: Dorsal paravertebral ve epidural bloğun torakotomi sonrası ağrı kontrolü ve solunum fonksiyonları üzerine etkilerini karşılaştırmaktı. Çalışma planı: Çalışmaya 50 hasta (38 erkek, 12 kadın; ort. yaş 49.8±17.7; dağılım 15-78) alındı. Hastalar rasgele epidural (grup 1) ve paravertebral (grup 2) blok uygulanacak şekilde iki gruba ayrıldı. Hastalara, hasta kontrollü analjezi (PCA) cihazıyla ek morfin uygulaması yapıldı. Ameliyat sonrası birinci günkü total morfin kullanımı PCA cihazının hafızasından not edildi. Görsel analog skalası (VAS) kullanılarak ilk 24 saatte, dinlenme sırasında; cerrahi yoğun bakım ünitesine gelişten bir saat sonra ve ardından her iki saatte bir hastalarda ağrı değerlendirilmesi yapıldı.Bulgular: İki grup arasında; VAS skoru ve morfin tüketimi açısından istatiksel olarak anlamlı fark bulunamadı. Ek olarak ameliyat sonrası birinci gündeki FEV1 ve FVC değerleri istatiksel olarak anlamlı derecede farklı değildi.Sonuç: Paravertebral blok torakotomi sonrası ağrı kontrolü için uygun ve etkili bir alternatif olabilir.
Torakotomi sonrası uygulanan dorsal paravertebral ve epidural bloğun ağrı kontrolü açısından karşılaştırılması
Background: The aim was to compare the effects of thoracic paravertebral and epidural blocks on pain relief and respiratory function after thoracotomy. Methods: 50 patients (38 males, 12 females; mean age 49.8±17.7; range 15 to 78 years) were included in the study. Patients were randomly divided into two groups to be applied epidural (group I), paravertebral (group II) block. Patients had supplementary doses of morphine by a patient-controlled analgesia (PCA) device. Postoperative total morphine consumption was noted by the PCA device. During the first 24 hours using visual analoque scale (VAS) patients were asked to assess their pain at rest; 1 hour after being in the intensive care unit and every 2 hoursResults: There were no significant differences between the groups regarding morphine consumption and VAS scores. Additionally, on the first postoperative day FEV1 and FVC measurements were not significantly different.Conclusion: Paravertebral block may be an effective and safe altenative for the pain relief after thoracotomy.
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- 1) Sabanathan S, Richardson J, Mearns AJ. Management of pain in thoracic surgery. Br J Hosp Med 1993;50:114-20.
- 2) Sabanathan S, Eng J, Mearns AJ. Alterations in respiratory mechanics following thoracotomy. J R Coll Surg Edinb 1990;35:144-50.
- 3) Catley DM, Thornton C, Jordan C, Lehane JR, Royston D, Jones JG. Pronounced, episodic oxygen desaturation in the postoperative period: its association with ventilatory pattern and analgesic regimen. Anesthesiology 1985;63:20-8.
- 4) Lehmann KA. Patient-controlled analgesia for postoperative pain. In: Benedetti C, Chapman CR, Giron G, editors. Advances in pain research and therapy. New York: Raven Press; 1990. p. 297-324.
- 5) Kavanagh BP, Katz J, Sandler AN. Pain control after thoracic surgery. A review of current techniques. Anesthesiology 1994;81:737-59.
- 6) Covino BG. Pharmacokinetic aspects of local anesthetic agents. In: Covino BG, Vasallo HG, editors. Local anesthetics. Mechanism of action and clinical use. New York: Grune & Stratton; 1976. p. 95-121.
- 7) Ross RA, Clarke JE, Armitage EN. Postoperative pain prevention by continuous epidural infusion. A study of the clinical effects and the plasma concentrations obtained. Anaesthesia 1980;35:663-8.
- 8) Rawal N, Arner S, Gustafsson LL, Allvin R. Present state of extradural and intrathecal opioid analgesia in Sweden. A nationwide follow-up survey. Br J Anaesth 1987;59:791-9.
- 9) Renck H. Neurological complications of central nerve blocks. Acta Anaesthesiol Scand 1995;39:859-68.
- 10) Hadzic A, Vloka JD. Thoracic paravertebral block. In: Hadzic A, Vloka JD, editors. Peripheral nerve blocks. Principles and practice. 1st ed. Columbus: Mc Graw Hill. 2004; 194-207.
- 11) Logas WG, el-Baz N, el-Ganzouri A, Cullen M, Staren E, Faber LP, et al. Continuous thoracic epidural analgesia for postoperative pain relief following thoracotomy: a random ized prospective study. Anesthesiology 1987;67:787-91.
- 12) Perttunen K, Nilsson E, Heinonen J, Hirvisalo EL, Salo JA, Kalso E. Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain. Br J Anaesth 1995;75:541-7.
- 13) Matthews PJ, Govenden V. Comparison of continuous paravertebral and extradural infusions of bupivacaine for pain relief after thoracotomy. Br J Anaesth 1989;62:204-5.
- 14) Richardson J, Sabanathan S, Jones J, Shah RD, Cheema S, Mearns AJ. A prospective, randomized comparison of preoperative and continuous balanced epidural or paravertebral bupivacaine on post-thoracotomy pain, pulmonary function and stress responses. Br J Anaesth 1999;83:387-92.
- 15) Sabanathan S, Mearns AJ, Bickford Smith PJ, Eng J, Berrisford RG, Bibby SR, et al. Efficacy of continuous extrapleural intercostal nerve block on post thoracotomy pain and pulmonary mechanics. Br J Surg 1990;77:221-5.
- 16) Bigler D, Dirkes W, Hansen R, Rosenberg J, Kehlet H. Effects of thoracic paravertebral block with bupivacaine versus combined thoracic epidural block with bupivacaine and morphine on pain and pulmonary function after cholecystectomy. Acta Anaesthesiol Scand 1989;33:561-4.
- 17) Richardson J, Sabanathan S. Thoracic paravertebral analgesia. Acta Anaesthesiol Scand 1995;39:1005-15.
- 18) Richardson J, Lonnqvist PA. Thoracic paravertebral block. Br J Anaesth 1998;81:230-8.
- 19) Conacher ID, Paes ML, Jacobson L, Phillips PD, Heaviside DW. Epidural analgesia following thoracic surgery. A review of two years’ experience. Anaesthesia 1983;38:546-51.
- 20) Gilbert J, Hultman J. Thoracic paravertebral block: a method of pain control. Acta Anaesthesiol Scand 1989;33:142-5.
- 21) Shaw WM. Medial approach for paravertebral somatic nerve block. J Am Med Assoc 1952;148:742-4.
- 22) Gilbert J, Schuleman S, Sharp T. Inadvertent paravertebral block. Anaesthesia 1989;44:527-8.