Spirulina is photosynthetic, filamentous, spiral-shaped, multicellular and green-blue microalga. The two most important species of which are Spirulina maxima and Spirulina platensis. Since its chemical composition includes proteins, carbohydrates, vitamins, minerals, essential fatty acids and pigments like chlorophyll a, carotenes and phycocyanin, it is considered an excellent food and feed. It also used in medicine and cosmetic industries. Because of its nutritional, medical and biological value, genetic studies on Spirulina have been increased all over the world to develop new strains gained new properties