Eno-Obong E. UTUK, Enobong E. IKPEME, Ifeoma J. EMODİ, Etim M. ESSİEN

Nijerya'da Uyo, Akwa Ibom Eyaleti'nde Bir Üçüncü Basamak Hastanede Trombosit sayısı Üzerine Falsiparum Sıtmasının Etkisi

AMAÇ: Sıtma Nijerya'da çocuklar arasında hastalık ve ölüm nedenleri arasında önemli bir yer tutmaktadır. Ttrombositopenik paternler hakkında yerel topluluklardaki bu çalışmanın amacı çocukluk çağı sıtmasının bu önemli komplikasyonu hakkında farkındalığı arttırmaktır. YÖNTEM: Yaşları altı ay ile 15 yaş arasındaki p. falciparum sıtması olan 180 çocuğun trombosit sayıları ile sıtma olmayan 180 sağlıklı çocuğun trombosit sayıları yaş ve cinsiyet açısından eşleştirilerek karşılaştırıldı. Trombosit sayıların otomatik analizör (Sysmex KX-21N) kullanılarak tespit edildi. BULGULAR: Ortalama trombosit sayıları deney ve kontrol grupları için sırasıyla 297,40±128,03 ve 338,27±103,89 x109/L idi. Aradaki fark istatistiksel olarak anlamlıydı (p

The Effect of Falciparum Malaria Infection on The Platelet Count of Children in a Tertiary Hospital in Uyo, Akwa Ibom State of Nigeria

AIM: Malaria is a major cause of illness and deaths in children in Nygeria. The aim of this research on thrombocytopenic patterns in local communities is to improve awareness of this important complication of childhood malaria. METHOD: The effect of p. falciparum malaria infection on the platelet count of one hundred and eighty children aged six months to fifteen years were compared with 180 healthy controls without malaria matched for age and gender. The platelet counts were evaluated using the automated analyser (Sysmex KX-21N). RESULTS: The mean platelet count (x109/L) for subjects and controls were 297.40±128.03 and 338.27±103.89 respectively. The difference was statistically significant (p < 0.001). There was a lower mean platelet count in those with severe malaria, with an inverse relationship between the malaria parasite density and platelet count (r=-0.21; p<0.001). CONCLUSION: The study demonstrated a higher level of thrombocytopenia in children presenting with severe manifestations of falciparum malaria in this setting. It is therefore important to monitor the platelet counts of children presenting with severe falciparum malaria.

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