Aylin Fidan KORCUM, Bülent V. AĞIRDIR, Gamze AKSU, Kenan GÜNEY, Oktay DİNÇ

Nazofarenks anjiyofibromlarında tedavi yaklaşımları

Nazofarenks anjiyofibromları özellikle ergenlik döne- minde erkeklerde nadiren görülen, sfenopalatin fora- menden köken alan benign, vasküler tümörlerdir. Lokal destrüktif büyüme özelliğinden dolayı ölümcül kanamalara, intrakraniyal uzanıma ve cerrahi sıra- sında kanama gibi yaşamı tehdit eden komplikas- yonlara neden olabilirler. Tedavide çok sayıda yön- teme başvurulmuş olmasına karşın, kabul edilebilir morbiditeleri nedeniyle etkili tedavi yöntemleri olarak sadece cerrahi ve eksternal radyoterapi uygulan- maktadır. Nazofarenks anjiyofibromlarının tedavisin- de erken evrede endoskopik cerrahinin kullanımıyla başarılı sonuçlar alınmakta, ileri evre ve nüks tümör- lerde ise radyoterapideki son teknolojik gelişmeler önemli avantajlar sağlamaktadır

Anahtar Kelimeler:

Anjiyofibirom/cerrahi/radyoterapi, embolizasyon, terapötik, endoskopi, nazofarengeal neoplaziler.

Treatment modalities of nasopharyngeal angiofibroma

Nasopharyngeal angiofibroma is a rare, benign vascular tumor originating from the sphenopalatine foramen. It primarily affects adolescent males. Due to its propensity to locally destructive growth, the tumor may lead to fatal epistaxis, intracranial extension, and life-threatening complications such as intraoperative hemorrhage. Many treatment modalities have been used for the management of nasopharyngeal angiofibroma, but surgery and external beam radiation therapy have proved to be the only effective treatment modalities with acceptable morbidity. While endoscopic surgery provides successful results for early stage tumors, recent technological advances in radiotherapy offer significant advantages in advance and recurrent tumors.

Keywords:

Angiofibroma/surgery/radiotherapy, embolization, therapeutic, endoscopy, nasopharyngeal neoplasms,

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