Tayfun TURAN, Nazan DOLU, Setenay CUĞ, Fahri BAYRAM

Polikistik over sendromlu hastalarda seks hormonlarının sempatik deri cevabına etkileri*

Polikistik over sendromu (PKOS), obezite, insülin direnci, hiperinsülinemi, hiperandrojenizm, hipertansiyon ve bunların yanısıra sempatik sinir sistemi aktivitesinde değişikliklerle karakterize, kompleks metabolik bir hasta- lıktır. Elektrodermal aktivite (EDA), deri iletkenlik seviye- sinde (DİS) değişikliğe neden olan sempatik kolinerjik sudomotor fonksiyonu yansıtır. Çalışmamızda, PKOSta değişiklik gösteren seks hormonları ile DİS arasındaki ilişki incelendi. Çalışmamız, 20 sağlıklı kontrol (ortalama yaş: 25.90±0.91 yıl) ve PKOSlu 29 hastada (ortalama yaş: 23.51±1.04 yıl) gerçekleştirildi. PKOSlu hasta grubunda; serbest testosteron (sT)(p

The effects of sex hormones on sympathetic skin response in patients with

Polycystic ovary syndrome (PCOS) is a com- plex endocrine and metabolic disorder associated with obesity, hyperandrogenism, hypertension, hyperinsulin- ism, insulin resistance and also characterized by changes in sympathetic nervous system activity. Electrodermal activity (EDA) reflects sympathetic activity which induces changes in skin resistance to electrical conduction. We studied the relationship between the skin conductance level (SCL) and sex hormone levels in PCOS. Twentynine patients with PCOS (mean age: 25.92±1.86 years) and twenty healthy women (mean age: 24.88±1.75 years) were included. Free testosterone (fT) (p

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