MİDE-BAĞIRSAK NEMATODLARIYLA (TRİCHOSTRONGYLİDAE) DOĞAL ENFEKTE KOYUNLARDA RİCOBENDAZOL’ÜN (RİCOBEN, ALKE) TEDAVİ ETKİNLİĞİ
Bu çalışma, Nevşehir yöresinde yetiştiriciliği yapılan
doğal enfekte koyunlarda ricobendazol (Ricoben,
Alke)’ün mide-bağırsak nematodlarına karşı tedavi etkinliğini değerlendirmek amacıyla yürütülmüştür. Bu
amaçla, Şubat-Mart 2018 tarihleri arasında Nevşehir
yöresinde bir koyunculuk işletmesinde mide-bağırsak
nematodları yönünden enfekte olan koyunlardan 50’si
gram dışkıdaki yumurta sayısı (EPG) dikkate alınarak
seçilmiştir. Koyunlar ilaç grubunda 40, kontrol grubunda ise 10 olmak üzere 2 gruba ayrılmış ve ilaç uygulamasından önce dışkı örnekleri alınmıştır. İlaç grubuna
üreticinin önerileri doğrultusunda 3,75mg/kg CA dozda
ricobendazol (Ricoben, Alke) enjektable olarak uygulanırken, kontrol grubuna herhangi bir uygulama yapılmamıştır. İlaç uygulaması sonrası 0., 7. ve 14. günlerde
her gruptan dışkı örnekleri toplanmış ve mide-bağırsak
nematodlarının EPG değerleri belirlenmiştir. Gruplar
arasında 0. gün için EPG değerleri arasında farklılık
bulunmazken (p>0,05), gruplar arasında ricobendazol
(Ricoben, Alke) uygulamasının 7. günde %99,2 etkinlik
gösterdiği ve bu etkinliğin 14. günde %100’e ulaştığı
tespit edilmiştir.
Sonuç olarak, bu çalışma ile doğal enfekte koyunlarda
mide-barsak nematodlarına karşı ricobendazol’ün tedavi etkinliğinin oldukça yüksek olduğu tespit edilmiştir.
This study was carried out to determine the treatment
efficacy of ricobendazole (Ricoben, Alke) against gastrointestinal nematodes infection in naturally infective
sheep in Nevsehir region. For this aim, fifty sheep which
were selected according to nematode egg per gram feces (EPG) infective with gastrointestinal nematodes
determined an enterprise located Nevsehir region between February and March 2018. The sheep were divided into two groups as 40 in the drug group and 10 in
the control group and fecal samples were collected from
each group before drug application. While drug group
was injected with 3.75 mg/kg dose of ricobendazole
(Ricoben, Alke) according to the manufacturer's recommendations, no drug was given to the control group.
Fecal samples were collected on the 0th, 7th and 14th
days after drug application and the EPG values were
calculated. While there was no difference between the
groups in EPG values at day 0 (p> 0.05), ricobendazole
(Ricoben, Alke) application was found to be 99.2% on
day 7 and this efficacy was 100% on 14th day.
As a result, it was determined that the treatment efficacy of ricobendazole against gastrointestinal nematode
infection was very high in naturally infected sheep.
___
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