HİSTOMORFOMETRİ VE MİKRO-BT ANALİZLERİNİN FARKLI YOĞUNLUKLARDAKİ KEMİKLERE YERLEŞTİRİLEN DENTAL İMPLANTLARIN KEMİK İMPLANT KONTAĞI YÜZDESİNİ BELİRLEMEDEKİ ETKİNLİĞİ

Genel Bilgi: Kemik içi dental implant tedavisindeimplantın stabilitesi ve osseointegrasyonun değerlendirilmesi, tedavisinin başarısı seviyesinin belirlenmesindeoldukça önemlidir. Bu parametrelerin değerlendirilmesinde ise, histomorfometrik analiz ve son dönemlerdepopüler olan Mikro-BT analizi ön plana çıkan analizlerdendir.Amaç:Bu çalışmada, implantların osseointegrasyonlarını değerlendirmek için kullanılan kemik-implant kontağ ı analizinde histomorfometrinin ve mikro-BT’ninavantajlarını, dezavantajlarını ve etkilerinin karşılaştırılması amaçlamıştır.Yöntem: 20 adet dişi tavşan, rastgele yalancı overektomi uygulanan (Grup 1 [yalancıOVX], n:1 0 ) ve bilateraloverektomi uygulanan (Grup 2 [OVX], n:10) gruplar olmak ü zere iki gruba ayrıldı. Tavşanların sağ tibial kemiklerine birer adet implant yerleştirildi. Sakriϐikasyonsonrası elde edilen verilerle, mikrotomograϐik incelemeve histomorfometrik analiz ile kemik-implant kontağ ıdeğ erlendirildi.Bulgular: Araştırma bulgularına göre, kemik implantkontağı incelemesinde mikro-BT ve histomorfometrikanalizden elde edilen veriler arasında güçlü, pozitif yönlü ve istatistiksel olarak anlamlı bir korelasyon olduğutespit edildi (r=0,6; p=0,005).Sonuç: Bu çalışma sonucunda, kemik-implant kontağıyüzdesini değerlendirmede mikro-BT vehistomorfometrik analizlerinin birlikte kullanımlarınındaha etkili olacağını belirlenmiştir.

THE EFFECT OF HISTOMORPHOMETRY AND MICRO-CT ANALYSIS ON DETERMINING THE PERCENTAGE OF BONE IMPLANT CONTACT IN DENTAL IMPLANTS PLACED ON BONES AT DIFFERENT DENSITY

Background: Osseointegration is important in the success of dental implants. Measurement of implant stability and osseointegration is important to evaluate the success of treatment. Here, histomorphometric and Micro-CT analysis are prominent. Objectives: The aim of this study was to compare the advantages, disadvantages and efficacy of histomorphometry and micro-CT in bone-implant contact analysis used to evaluate the osseointegration of implants. Methods: 20 female rabbits were randomly divided in to two groups: group 1 (shamOVX, n:10) and group 2 bilateral-ovariectomized (OVX, n:10). One implant was placed on the right tibial bones of the rabbits. Microtomographic analysis and histomorphometric analysis were performed with the data obtained after sacrification. Results:As a result of the study, a strong, positive and statistically significant correlation was found between the data obtained from micro-CT and histomorphometric analysis in bone-implant contact (r=0.6, p=0.005). Conclusion:The results of this study showed that the use of micro-CT and histomorphometry together in evaluating the percentage of bone-implant contact would be more effective.

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