Yoğun bakımda mekanik ventilasyon uygulanan hastalarda sedasyon ve analjezi

Yoğun bakımda entübe takip edilen hastaların mekanik ventilasyona uyum sağlamaları çoğu zaman medikal destek gerektirir. Uygun sedasyonun uygulanmaması bu hastalarda tedavi başarısızlığına neden olacaktır.  Bu nedenle yoğun bakım hekimleri sedasyon ve analjezi sağlamak için bazı ajanlara başvurabilirler. Ajanların seçimleri hastanın hemodinamisi, kafa içi basıncı,  havayolu dinamikleri, ilacı metabolize edebilme durumu gibi birçok durum göz önünde bulundurularak yapılır. Bu derlemede bu amaçla en sık kullanılan ajanlar ve ajanların tercih edilme ya da edilmeme nedenlerinden bahsedilecektir.

Sedation and analgesia in patients who need mechanical ventilation in intensive care unit

Entubated patients in intensive care unit usually needs medical support to  be in harmony with mechanical ventilation. Failure to apply proper sedation will result in treatment failure in these patients. For this reason, intensive care physicians may apply to some agents to provide sedation and analgesia. The choice of agents is based on many factors such as the patient's hemodynamics, intracranial pressure, airway dynamics, drug metabolism. In this review, the most commonly used agents for this purpose and the reasons why agents are preferred or not will be mentioned.

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