Oral kavitede görülen invaziv kanserler / Invasıve cancers of the oral cavıty

Ağız kanseri, dünyada en sık görülen 6. kanser olup, tüm dünyada kanserle ilişkili ölümlerde erkekler arasında 20. sırada, kadınlar arasında ise 16. sırada yer almaktadır. Tüm ağız boşluğu kanserlerinin %90'ından fazlası oral skuamöz hücreli karsinomdur. Oral kanser orta yaşlı bireylerde sık görülmektedir. İnsidans yaşla birlikte artmaktadır. Ağız kanseri genellikle asemptomatiktir. İlk belirtileri kızarık alanlar, küçük mukozal büyümeler veya ülserasyonlar şeklinde olmaktadır. İleri evrede tümör kas, kemik veya cilt gibi komşu dokulara infiltre olmakta ve bölgesel lenf nodlarına yayılım göstermektedir. Bölgesel lenf nodu metastazı prognozu kötüleştirmektedir. Bu derlemede, skuamöz hücreli karsinom ile verrüköz karsinom, malign melanom, primer intraosseöz skuamöz hücreli karsinom gibi ağız kavitesinde görülen diğer invaziv kanserler ve tedavileri ile ilgili bilgi vermeyi amaçladık.

Anahtar Kelimeler:

ağız kanseri, skuamöz hücreli karsinom, malignansi, invaziv kanserler

Invasive cancers of the oral cavity: review

Oral cancer is the sixth most common cancer worldwide. Globally, therefore, ‘oral cancer’ is the twelfth most frequent cause of cancer related deaths amongst males and sixteenth amongst females. Oral cancer is common in middle-aged adults. Incidence increases with age. More than 90% of oral malignancies are oral squamous cell carcinoma. Oral cancer is asymptomatic in general. Early mucosal lesions seem as reddish areas, small mucosal growths or ulcerations. In late stage, tumor infiltrates to contiguous tissues such as muscle, bone or skin and evolves to regional lymph nodes. Metastasis to regional lymph nodes considered as poor prognosis. In this review, we aimed to give information about squamous cell carcinoma and other invasive cancers of oral cavity such as verrucous carcinoma, malign melanoma, primary intraosseous squamous cell carcinoma and their treatments.

Keywords:

Oral cancer squamous cell carcinoma, malignancy, invasive cancers, verrucous carcinom,

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