Bilge KESİKBURUN, Nuray GÜLGÖNÜL, Emel EKŞİOĞLU, Aytül ÇAKICI

MİGREN TEDAVİSİNDE AKUPUNKTURUN ETKİNLİĞİ

Amaç: Migren, sıklıkla genç üretken populasyonu etkileyen, tekrarlayan baş ağrısı ile karakterize önemli bir dizabilite nedenidir. Atak sayısı ile ilişkili olarak kişinin yaşam kalitesini azaltmaktır. Tedavide farmakalojik ve nonfarmakolojik tedavi yöntemleri kullanılmaktadır. Bu çalışmanın amacı migren hastalarında nonfarmakolojik bir tedavi yöntemi olarak akupunkturun etkinliğini incelemektir. Materyal ve Metot: Çalışmaya migren tanısı bulunan 35 hasta (ortalama yaş, 38.9±11.0 yıl) dahil edildi. Hastalara haftada bir kez, 30 dakika süren, toplam 10 seans akupunktur uygulandı. Hastalarda başlangıç ve 3. ay’da VAS (vizüel analog skala) ağrı skoru, MIDAS (Migraine Disability Assesment Scale), SF-36 (Short Form-36), BDÖ (Beck Depresyon Ölçeği) ve akut ağrı için kullanılan migren ilacı sayısı değerlendirildi. Bulgular: Hastalarda tedavi öncesine (8.2±1.3) göre, akupunktur ile tedavisi sonrası (4.4±1.3) VAS ağrı skorlarında anlamlı azalma görüldü (p=0.005). Ayrıca çalışma süresince akut ağrı için kullanılan ortalama ilaç sayısında anlamlı azalma saptandı (tedavi öncesi, 2.1±1.7; tedavi sonrası, 8.7±6.4; p 0.001). Tedavi sonrası MIDAS ve BDÖ değerlendirmelerinde anlamlı iyileşme bulundu (her ikisi için p 0.001). SF-36 yaşam kalitesi parametrelerinde anlamlı düzeyde artış görüldü. (p 0.05). Ciddi bir yan etki saptanmadı. Sonuç: Akupunkturun migrende ağrı, kullanılan ilaç sayısı, dizabilite, depresyon ve yaşam kalitesi üzerine olumlu etkileri olabilir. Akupunktur düşük yan etki profili ile etkili bir modalite olarak, migren tedavisinde nonfarmakolojik seçenekler arasında düşünülebilir.

EFFECTIVENESS OF ACUPUNCTURE IN THE TREATMENT OF MIGRAINE

Aim: Migraine is an important cause of disability characterized by recurrent headache, frequently affecting the young productive population. It decreases quality of life in association with frequency of acute attack. pharmacological or non-pharmacogical therapies are used in the treatment. The aim of this study was to asses effectiveness of acupuncture as a non-pharmacogical therapy in patients with migraine Materials and Methods: 35 patients diagnosed as having migraine (mean age, 38.9±11.0 years) were included in the study. The acupuncture was performed one session in a week, lasting 30 minutes, sum of 10 session. Visual analog scale (VAS) pain score, MIDAS (Migraine Disability Assessment Scale), SF-36 (Short Form-36), BDI (Beck Depression Inventory), and count of intake medication for acute pain relief was assessed at the baseline and 3rd months. Results: VAS pain scores decreased significantly at 3rd months after acupuncture treatment (4.4±1.3) compared to baseline (8.2±1.3) (p=0.005). In addition, count of intake medications for acute pain relief was significantly decreased (before treatment, 8.7±6.4; after treatment 2.1±1.7; p 0.001). The significant improvement for MIDAS and BDI scores were found after the treatment (for both p 0.001). Significant increase was shown in SF-36 parameters (p 0.05). No severe adverse effect was detected. Conclusion: Acupuncture may have positive effects on pain, count of intake medication, disability, depression and quality of life in migraine. Acupuncture as an effective modality with low side effect profile may be considered among nonpharmacogical options in the treatment of migraine.

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