Bir köpeğin uterusunda malign osteoklast-benzeri dev hücreli tümör

Bu vaka raporunda 10 yaşlı, dişi, Setter ırkı, bir köpekte uterusta nadir gözlenen osteoklast-benzeri dev hücreli tümör bildirilmiştir. Makroskobik olarak 27x24x11 cm ölçülen tümöral kitle serviks tabanında yer alıyordu. Histopatolojik olarak atipik iğ-küresel şekilli yüksek mitotik aktiviteye sahip hücreler ile dağınık halde osteoklast benzeri çok çekirdekli dev hücreler gözlendi. Tümör hücreleri vimentin, CD 117, LCA antikorları ile pozitif boyandı. Bunun tersine, aynı hücreler sitokeratin, CD 34, S100 ve SMA antikorları ile boyanmadı Bu bir köpeğin uterusunda ilk defa bildirilen malign osteoklast-benzeri dev hücreli tümördür.

Keywords:

Köpek osteoklast-benzeri dev hücre, tümör,

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