The effects of respiratory functions on disease activity, functionality, spinal mobility and quality of life in patients with ankylosing spondylitis

We aimed to determine the relationship between the pulmonary functions with disease activity, functionality, spinal mobility and quality of life in patients with ankylosing spondyilitis (AS). PATIENTS AND METHOD: 52 patients (44 male, 8 female) who were diagnosed as AS in Şişli Etfal Education and Research Hospital physical medicine and rehabilitation policlinics according to the Modified New York criteria, participated in our study. The demographic characteristics and smoking habbits were questioned, the chest expansion was measured. The functional activity, disease activity, spinal mobility measurement were evaluated by BASFI, BASDAI,BASMI (Bath Ankylosing Spondylitis functional, disease activity, metrology ındex),and the life quality was evaluated by life quality spesific to the disease (ASQOL). The respiratory functions were measured by spirometry. 52 patients in 31 patients restrictive, and in 1 patient mixed pattern pulmonary involvement were detected. There was no determined no significant difference between who detected and not detected restrictive lung disease regarding age, gender, body mass index, lung expansion (LE), history of smoking (p>0.005). Pulmonary function tests results and LE of smoker and no smoker patients were similar. While LE was found to be positively correlated with FEV1 and FVC (p

___

1. Diagnosis and treatment of rheumatic diseases. Göksoy T , editor. Yüce Yayım; 2001. p. 622-43.

2. Kabasakal Y. Ankylosing spondylitis. In: Gümüşdiş G, Doğanavşargil E, eds, Handbook of Clinical Rheumatology. Ankara: Güven Kitabevi, 2003;504-16.

3. Braun J, Sieper J. Ankylosing spondylitis. Lancet. 2007;369(9570):1379-90.

4. Tanoue LT. Pulmonary involvement in collagen vascular disease. A review of the pulmonary manifestations of the Marfan syndrome, ankylosing spondylitis, Sjögren's syndrome and relapsing polychondritis. J Thorac Imaging. 1992;99:7(2):62-7.

5. Calin A, Garrett S, Whitelock H, Kennedy LG, O'Hea J, Mallorie P, Jenkinson T. A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol. 1994;21(12):2281-5.

6. Karatepe AG, Akkoc Y, Akar S, Kirazli Y, Akkoc N. The Turkish versions of the Bath Ankylosing Spondylitis and Dougados Functional Indices: reliability and validity. Rheumatol Int. 2005;25(8):612-8.

7. Akkoc Y, Karatepe AG, Akar S, Kirazli Y, Akkoc N. A Turkish version of the Bath Ankylosing Spondylitis Disease Activity Index: reliability and validity. Rheumatol Int. 2005;25(4):280-4.

8. Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol. 1994;2112:2286-91.

9. Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A. Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol. 1994;21(9):1694-8.

10. Duruöz MT, Doward L, Turan Y Cerrahoglu L, Yurtkuran M, Calis M, Tas N, Ozgocmen S, Yoleri O, Durmaz B, Oncel S,Tuncer T, Sendur O, Birtane M, Tuzun F, Bingol U, Kirnap M, Celik Erturk G, Ardicoglu O, Memis A, Atamaz F, Kizil R, Kacar C, Gurer G, Uzunca K, Sari H. Translation and validation of the Turkish version of the Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire. Rheumatol Int. 2013;33(11):2717-22.

11. Dincer U, Cakar E, Kıralp MZ, Bozkanat E, Kılac H, Dursun H. Pulmonary effects of ankylosing spondylitis and its impact on functionality and quality of life. Tohoku J Exp Med. 2007;212(4):423-30.

12. Şendur F, Karadağ F, Çildağ O, Başar A, Yıldırım T. The Evaluation of Pulmonary Findings of Ankylosing Spondylitis by Chest Radiography, Pulmonary Function Tests and High Resolution Computed Tomography. Tur Torax Der. 2001;2:50-2.

13. Sampaio-Barros PD, Cerqueira EM, Rezende SM, Maeda L, Conde RA, Zanardi VA, Bértolo MB, de Menezes Neto JR,Samara AM. Pulmonary involvement in ankylosing spondylitis. Clin Rheumatol. 2007;26(2):225-30.

14. Casserly IP, Fenlon HM, Breatnach E, Sant SM. Lung findings on high-resolution computed tomography in idiopathic ankylosing spondylitis-correlation with clinical findings, pulmonary function test in gand plain radiography. Br J Rheumatol. 1997;36(6):677-82.

15. Altin R, Ozdolap S, Savranlar A, Sarikaya S, Tor M, Kart L, Ozdemir H. Comparison of early and late pleuropulmonary findings of ankylosing spondylitis by high-resolution computed tomography and effects on patients daily life. Clin Rheumatol. 2005;24(1):22-8.

16. Fisher LR, Cawley MI, Holgate ST. Relation between chest expansion, pulmonary function, and exercise tolerance in patients with ankylosing spondylitis. Ann Rheum Dis. 1990;49(11):921-5.

17. Feltelius N, Hedenström H, Hillerdal G, Hallgren R. Pulmonary involvement in ankylosing spondylitis. Ann Rheum Dis. 1986;45(9):736-40.

18. Remy-Jardin M, Remy J, Boulenguez C, Sobaszek A, Edme JL, Furon D. Morphologic effects of cigarette smoking on airways and pulmonary parenchyma in healthy adult volunteers: CT evaluation and correlation with pulmonary function tests. Radiology. 1993;186(1):107-15.

19. Baser S, Cubukcu S, Ozkurt S, Sabir N, Akdag B, Diri E. Pulmonary involvement starts in early stage ankylosing spondylitis. Scand J Rheumatol. 2006;35(4):325-7.

20. Ozgul A, Peker F, Taskaynatan MA, Tan AK, Dinçer K, Kalyon TA. Effect of ankylosing spondylitis on health-related quality of life and different aspects of social life in young patients. Clin Rheumatol. 2006;25(2):168-74.

21. Ward MM, Weisman MH, Davis JC Jr, Reveille JD. Risk factors fo function allimitations in patients with long-standing ankylosing spondylitis. Arthritis Rheum. 2005;53(5):710-7.

22. El Maghraoui A, Chaouirs S, Abid A, Bezza A, Tabache F, Achemlal L, Abouzahir A, Ghafir D, Ohayon V, Archane MI. Lung finding on throcic high resolution computed tomography in patients with ankylosing spondylitis correlations with disease duration, clinica findings and pulmonary function testing. Clin Rheumatol. 2004;23(2):123-8.

23. Cerrahoğlu L, Unlu Z, Can M, Goktan C, Çelik P. Lumbar stifness but not thoracic radiographic changes relate to alteration of lung function tests in ankylosing spondylitis. Clin Rheumatol. 2002;21(4):275-9.

24. Uzunca K, Özdemir F. Evaluation of clinical activity and functiona limpairment in smokers with ankylosing spondylitis. Rheumatol Int. 2005;25(5):357-360.

25. Durmuş B, Altay Z, Baysal Ö, Ersoy Y, Hacıevliyagil SS, Baysal T, Aytemur ZA, Doğan E. Ankilozan spondilitli hastalarda yaş ve cinsiyete göre düzeltilmiş göğüs ekspansiyonunun klinik pratikte kullanımı. Turk J Phys Med Rehab. 2011;57(3):128-33.

26. Soyyigit S, Erk M, Güler N, Kilinç G. The value of SF-36 questionnaire for the measurement of life quality in chronic obstructive pulmonary disease. Tuberk Toraks. 2006;54(3):259-66.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

Peritoneal dialysis–related peritonitis with an unexpected micro-organism: enterococcus hirae

Dilek Barutcu ATAS, Basar AYKENT, Ebru AŞICIOĞLU, Hakkı ARIKAN, Arzu VELIOGLU, Serhan TUĞLULAR, Çetin ÖZENER

Two siblings with familial subclinical hyperthyroidism with unknown etiology

Elif ÖZSU, Gul Yesiltepe MUTLU, Filiz Mine ÇİZMECİOĞLU, Rifat BİRCAN, Şükrü HATUN

Severe major depression: A case of neurobrucellosis

Lara Utku INCE, Nursel Akti KAVURAN, Abdulcemal ÖZCAN, SÜHEYLA ÜNAL

Rett Syndrome and anaesthetic management: a case report

Ömer KARACA, Hüseyin Ulaş PINAR, Saziye Ebru EKMEKCİOGLU, Rafi DOĞAN

General anesthesia management in carotid endarterectomy surgery: a single center experience

Ahmet Selim ÖZKAN, SEDAT AKBAŞ, MEHMET AKİF DURAK, Osman KAÇMAZ, Mehmet Özcan ERSOY, MAHMUT DURMUŞ

The incidence of demodex in the Faculty of Science Students and measurement of these Students' knowledge level about demodex

SERPİL ŞENER, ÜLKÜ KARAMAN, GÜLDEN HAKVERDİ

Application of next generation sequencing in forensic science

GÖNÜL FİLOĞLU TÜFEK, Irmak SAH, Muhammed DOĞAN, Sila Bulut NALCAOGLU, ÖZLEM BÜLBÜL, Ilksen TAVACİ, TUĞBA ÜNSAL SAPAN

Mucinous cystadenoma of the appendix causing chronic intermittent right iliac fossa pain: case report

Serkan ÜNLÜ, Reyhan KARAGUL, Metin DOĞAN

Transient neonatal diabetes with fanconi bickel syndrome

Elif ÖZSU, Cengiz KARA, Gülay Can YILMAZ, Derya TEPE, Murat AYDIN

Pattern and risk factors of childhood injuries at Emergency Department of Suez Canal University Hospital

Hussein Aamer AWAAD