Adnan Yalçın DEMİRCİ, Kazım YİĞİTKANLI, Fatih AYDEMİR

Incidence of symptomatic adjacent vertebral fractures after percutaneous balloon kyphoplasty in osteoporotic vertebral fractures

To investigate the long-term outcome of 203 patients with osteoporotic vertebra fractures who were treated with percutaneous kyphoplasty (PKP) technique under local anesthesia. Magnetic resonance and Computed Tomography Image results were used and correlated with clinical presentations to identify the symptomatic vertebral acute fracture levels. Percutaneous kyphoplasty was performed under local anesthesia/sedation technique in these patients. During the follow-up, pain symptoms were recorded on a self-reported visual analog scale (VAS). 203 patients (78 males and 125 females) with traumatic osteoporotic vertebral fractures in our clinic between 2015 and 2020. Patients’ VAS scores significantly decreased from 8.48±1.1 to 3.30±1.89 after 10 days of treatment (p

PDF

___

1. Hackbarth CB, Vogl TJ, Naguib N, et al. Long-term evaluation of pain reduction after vertebroplasty and kyphoplasty. Acta Radiol Open. 2021;30;10:1-7., 2. Noriega DC, Rodrίguez-Monsalve F, Ramajo R, et al. Long-term safety and clinical performance of kyphoplasty and SpineJack procedures in the treatment of osteoporotic vertebral compression fractures: a pilot, monocentric, investigator-initiated study. Osteoporos Int. 2019;30:637-5.
3. Civelek E, Cansever T, Yilmaz C, et al. The retrospective analysis of the effect of balloon kyphoplasty to the adjacent-segment fracture in 171 patients. J Spinal Disord Tech. 2014;27:98-104.
4. Cagli S, Isik HS, Zılelı M. Vertebroplasty and kyphoplasty under local anesthesia: review of 91 patients. Turk Neurosurg. 2010;20:464-9.
5. Pflugmacher R, Schroeder RJ, Klostermann CK. Incidence of adjacent vertebral fractures in patients treated with balloon kyphoplasty: two years' prospective follow-up. Acta Radiol. 2006;47:830-40.
6. Farrokhi MR, Alibai E, Maghami Z. Randomized controlled trial of percutaneous vertebroplasty versus optimal medical management for the relief of pain and disability in acute osteoporotic vertebral compression fractures. J Neurosurg Spine. 2011;14:561-9.
7. Klazen CA, Lohle PN, de Vries J, et al. Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): An open-label randomised trial. Lancet. 2010;376:1085-92.
8. Rousing R, Andersen MO, Jespersen SM, Thomsen K, Lauritsen J.Percutaneous vertebroplasty compared to conservative treatment in patients with painful acute or subacute osteoporotic vertebral fractures: Threemonths follow-up in a clinical randomized study. Spine. (Phila Pa 1976) 2009;34:1349-54.
9. Bouza C, Lopez T, Magro A, et al. Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures: A systematic review. Eur Spine J. 2006;15:1050-67.
10. Fribourg D, Tang C, Sra P, et al. Incidence of subsequent vertebral fracture after kyphoplasty. Spine. 2004;29:2270-6.
11. Hillmeier J, Grafe I, Da Fonseca K, et al. The evaluation of balloon kyphoplasty for osteoporotic vertebral fractures. An interdisciplinary concept. Orthopade. 2004;33:893-904.
12. Faloon MJ, Ruoff M, Deshpande C, et al. Risk factors associated with adjacent and remote-level pathologic vertebral compression fracture following balloon kyphoplasty: 2-year follow-up comparison versus conservative treatment. J Long Term Eff Med Implants. 2015;25:313-9.
13. Chen LH, Lai PL, Chen WJ. Current status of vertebroplasty for osteoporotic compression fracture. Chang Gung Med J. 2011;34:352-9.
14. Zhang H, Xu C, Zhang T, et al. Does Percutaneous Vertebroplasty or Balloon Kyphoplasty for Osteoporotic Vertebral Compression Fractures Increase the Incidence of New Vertebral Fractures? A Meta-Analysis. Pain Physician. 2017;20:13-28.
15. Grados F, Depriester C, Cayrolle G, et al, Long- term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford). 2000;39:1410-4.
16. Uppin AA, Hirsch JA, Centenera LV, et al. Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology. 2003;226:119-24.
17. Harrop JS, Prpa B, Reinhardt MK, Lieberman I. Primary and secondary osteoporosis’ incidence of subsequent vertebral compression fractures after kyphoplasty. Spine. 2004;29:2120-5.
18. Baroud G, Nemes J, Heini P, Steffen T. Load shift of the intervertebral disc after a vertebroplasty: a finite-element study. Eur Spine J. 2003;12:421-6.
19. Rohlmann A, Zander T, Bergmann G. Spinal loads after osteoporotic vertebral fractures treated by vertebroplasty or kyphoplasty. Eur Spine J. 2006;15:1255-64.
20. Berlemann U, Ferguson SJ, Nolte LP, Heini PF. Adjacent vertebral failure after vertebroplasty. A biomechanical investigation. J Bone Joint Surg Br. 2002;84:748-52.
21. Kim SH, Kang HS, Choi JA, Ahn JM. Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol. 2004;45:440-5.
22. Luo J, Adams MA, Dolan P. Vertebroplasty and kyphoplasty can restore normal spine mechanics following osteoporotic vertebral fracture. J Osteoporos. 2010;20:729257.
23. Belkoff SM, Mathis JM, Jasper LE, Deramond H. The biomechanics of vertebroplasty: the effect of cement volume on mechanical behavior. Spine. 2001;26:1537-41.