Dose Addition of Tramadol to Levobupivacaine Femoral Nerve Block Prolong Its Analgesic Efficacy in Patients Undergoing Anterior Cruciate Ligament Reconstruction?

This study was designed to evaluate the effect of addition of tramadol to levobupivacaine femoral nerve block in patients undergoing anterior cruciate ligament reconstruction under general anaesthesia. 60 male patients ASA I-II aged 18-45 years, scheduled for anterior cruciate ligament reconstruction under general anaesthesia, patients were randomly allocated into two equal sized groups using closed envelope technique: Group L: (n= 30) femoral nerve block with levobupivacaine (0.5%) 20ml. Group LT: (n= 30) femoral nerve block with levobupivacaine (0.5%) 20ml +2mg/kg tramadol. Time to first request of postoperative analgesia, severity of postoperative pain at rest using VAS, dose of pethidine consumed in 24 h were recorded. There were no statistical significant differences between the two studied groups as regard to patient characteristics, time to first request of postoperative analgesia, postoperative pethidine consumption and 24 hours VAS at rest between the two studied group. The addition of tramadol 2mg/kg did not improve postoperative analgesic efficacy of levobupivacaine (0.5%) femoral nerve block in patients undergoing anterior cruciate ligament reconstruction under general anaesthesia.

___

1. Tran KM, Ganley TJ, Wells L, Ganesh A, Minger KI, Cucchiaro G:Intraarticular bupivacaine-clonidine-morphine versus femoral-sciatic nerve block in pediatric patients undergoing anterior cruciate ligament reconstruction. Anesth Analg. 2005;101(5):1304-10.

2. Anns JP, Chen EW, Nirkavan N, McCartney CJ, Awad IT. A comparison of sartorius versus quadriceps stimulation for femoral nerve block: a prospective randomized double-blind controlled trial. Anesth Analg. 2011;112(3):725-31.

3. Pham Dang C, Lelong A, Guilley J, Nguyen JM, Volteau C, Venet G, Perrier C, Lejus C, Blanloeil Y. Effect on neurostimulation of injectates used for perineural space expansion before placement of a stimulating catheter: normal saline versus dextrose 5% in water. Reg Anesth Pain Med. 2009;34(5):398-403.

4. Dauri M, Fabbi E, Mariani P, Faria S, Carpenedo R, Sidiropoulou T, Coniglione F, Silvi MB, Sabato AF. Continuous femoral nerve block provides superior analgesia compared with continuous intra-articular and wound infusion after anterior cruciate ligament reconstruction. Reg Anesth Pain Med. 2009;34 (2):95- 9.

5. Movafegh A, Razazian M, Hajimohamadi F, Meysamie A. Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade. Anesth Analg. 2006;102 (1):263-7.

6. Narang S, Dali JS, Agarwal M, Garg R. Evaluation of the efficacy of magnesium sulphate as an adjuvant to lignocaine for intravenous regional anaesthesia for upper limb surgery. Anaesth Intensive Care. 2008;36(6):840-4.

7. Alayurt S, Memis D, Pamukcu Z. The addition of sufentanil, tramadol or clonidine to lignocaine for intravenous regional anaesthesia. Anaesth Intensive Care. 2004;32(1):22-7.

8. Sen S, Ugur B, Aydin ON, Ogurlu M, Gursoy F, Savk O. The analgesic effect of nitroglycerin added to lidocaine on intravenous regional anesthesia. Anesth Analg. 2006;102(3):916-20.

9. Budd K, Langford R. Tramadol revisited. Br J Anaesth. 1999;82(4):493-5.

10. Tsai YC, Chang PJ, Jou IM. Direct tramadol application on sciaticnerve inhibits spinal somatosensory evoked potentials in rats. Anesth Analg. 2001;92(6):1547- 51.

11. Mert T, Gunes Y, Guven M, Gunay I, Gocmen C. Differential effects of lidocaine and tramadol on modified nerve impulse by 4-aminopyridine in rats. Pharmacology. 2003;69(2):68-73.

12. De Cosmo G, Mascia A, Clemente A, Congedo E, Aceto P. Use of levobupivacaine for the treatment of postoperative pain after thoracotomies. Minerva Anestesiol. 2005;71(6):347-51.

13. Kumar M, Kumar Batra Y, Panda NB, Rajeev S, Nagi ON. Tramadol added to bupivacaine does not prolong analgesia of continuous psoas compartment block. Pain Practice. 2009;9(1):43-50.

14. Mannion S, O'Callaghan S, Murphy DB, Shorten GD. Tramadol as adjunct to psoas compartment block with levobupivacaine 0.5%: a randomized doubleblinded study. Br J Anaesth. 2005;94(3):352-6.

15. Robaux S, Blunt C, Viel E, Cuvillon P, Nouguier P, Dautel G, Boileau S, Girard F, Bouaziz H. Tramadol added to 1.5% mepivacaine for axillary brachial plexus block improves postoperative analgesia dose-dependently. Anesth Analg. 2004;98(4):1172-7.

16. Kapral S1, Gollmann G, Waltl B, Likar R, Sladen RN, Weinstabl C, Lehofer F. Tramadol added to mepivacaine prolongs the duration of an axillary brachial plexus blockade. Anesth Analg. 1999;88(4):853-6.

17. Kaabachi O, Ouezini R, Koubaa W, Ghrab B, Zargouni A, Ben Abdelaziz A. Tramadol as an adjuvant to lidocaine for axillary brachial plexus block. Anesth Analg. 2009;108(1):367-70.

18. Aref AA. Effects of adding tramadol to 0.5% ropivacaine for interscalene brachial plexus block. Eg J Anaesth. 2006;22(2):140-3.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

Henoch-Schönlein Purpurasına Bağlı Şiddetli Rabdomiyoliz: Bir vaka takdimi [Turkish]

Mehmet İbrahim TURAN, Atilla ÇAYIR

Afşin Devlet Hastanesinde, İdrar Örneklerinden İzole Edilen Toplum Kaynaklı Escherichia Coli Suşlarının Antimikrobiyal Direnç Durumu ve GSBL Varlığının Araştırılması

YÜCEL DUMAN, İLKAY BOZKURT, MEHMET SAİT TEKEREKOĞLU

Novel Triage for Crowded Emergency Clinics: Patient Triage

Mehmet Husamettin AKKUCUK, MELTEM AKKAŞ, Nalan Metin AKSU, Evvah KARAKILIÇ, Hayri RAMADAN, Murat Dogan ISCANLİ, Yesim Cetinkaya SARDAN

The Effect of 6-weeks Military Training on Blood Hematological Parameters in Untrained Recruits in a Military University

Justin GNANOU, Brinnell CASZO, Igor KHALİN, Shahidah LEONG, Victor Feizal KNİGHT, Mohd Zin Bin BİDİN

Malatya'da Yarı Kırsal Bir Bölgede Ergenlerde Boyun Eğici Davranış ile Fiziksel Şiddete Maruziyet Asındaki İlişki

BELİZ YEKELER, ERKAN PEHLİVAN

Atipik Tiroid Fonksiyon Testleri: Tiroid Hormon Direnci

SONER CANDER, ÖZEN ÖZ GÜL, CANAN ERSOY

Üniversite Öğrencilerinin Bitkisel Ürünleri Kullanım Özelliklerinin Değerlendirilmesi

Mustafa Haki SUCAKLI, Soner ÖLMEZ, Hamit Sırrı KETEN, Cem YENİCESU, Nagihan Sarı SARI, MUSTAFA ÇELİK

Episodic Alcohol Consumption by Youths

Vladimir Alexeevich PEREVERZEV

The Impact of Early Versus Late Amniotomy on Duration of Labor, Maternal and Neonatal Outcomes in Iraqi Primigravida with Spontaneous Labor

Faris Anwer RASHEED, Alyaa Aziz AHMED, Saad Abdulrahman HUSSAİN

The Use of Gluteal Subfascial Implant for Gluteal Atrophy due to Injection: A Case Report

Meltem AYHAN, Soysal BAŞ, Cem ASLAN, Murat TUZUNER