Murathan ERKENT, Emre KARAKAYA

Sekonder Hiperparatiroidi Olgularında Tercih Edilen Cerrahi Tekniklerinin Uzun Dönem Klinik Sonuçlarının Karşılaştırılması

Amaç: Sekonder hiperparatiroidi (SHPT) kronik böbrek yetmezliği hastalarında (CKD) görülen bozulmuş kalsiyum-fosfor metabolizması ile karakterizedir. SHPT’nin rekürrensi, semptomların tekrarlamasına neden olabilir. Bu çalışmanın amacı subtotal paratiroidektomi (SPTX) ile total paratiroidektomi ile birlikte ototransplantasyon (PTX-AT) yöntemlerinin 5 yıllık klinik sonuçlarını karşılaştırmaktır. Gereç ve Yöntemler: SHPT nedeni ile Ocak 2000 ile Ekim 2020 tarihleri arasında ameliyat edilen 140 hastayı geriye dönük olarak taradık. Hastaların klinik vedemografik özellikleri, ameliyat öncesi ve ameliyat sonrası (1. gün, 1. ay, 6. ay, 1. yıl, 5. yıl) serum PTH, kalsiyum (Ca), fosfor (P) değerleri ve hastane yatış süreleri yapılan ameliyatlar açısından karşılaştırıldı. Veri normal dağılımları Shapiro-Wilks testi ile değerlendirildi. Araştırma gruplarına göre sayısal ölçümlerin karşılaştırılması veri dağılımına uygun olarak Mann-Whitney U test ile değerlendirildi. Araştırma gruplarına göre oran karşılaştırmaları veya ilişki araştırmaları ki-kare veya Fisher Exact test ile araştırıldı. P

Comparison of Long-term Clinical Outcomes of the Preferred Surgical Techniques in Secondary Hyperparathyroidism Cases

Objective: Secondary hyperparathyroidism (SHPT), that progresses with the deterioration of calcium-phosphorus metabolism detected in chronic kidney disease patients. Recurrence of SHPT may result in the recurrence of symptoms. Our aim was to compare the 5-year clinical results of autotransplantation after total parathyroidectomy (PTX-AT) with subtotal parathyroidectomy (SPTX). Materials and Methods: We analyzed 140 patients retrospectively from January 2000 and October 2020 who were operated due to SHPT. Clinical and demographic characteristics of the patients, preoperative and postoperative (1st day, 1st month, 6th month, 1st year, 5th years) serum PTH, calcium (Ca), phosphorous (P) values and length of hospital stay (LOS) were compared in terms of operations performed. The Shapiro-Wilks test was used for analyzing normally distributed datas. MannWhitney U test used to evaluate of comparison of numerical data. Fisher’s Exact or chi-square test was used for ratio comparisons or correlation. P

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