Hanisuhana HAMİDON, Deny SUSANTİ, Muhammad TAHER, Zainul Amiruddin ZAKARİA

Garcinia atroviridis – A review on phytochemicals and pharmacological properties

Garcinia atroviridis or commonly named as ‘Asam Gelugur’ among locals is extensively used as flavouring agent to provide sour sensation. Apart from being used as flavouring agent, G. atroviridis is also used in many ways to promote health traditionally. Previous investigations of the plant reported many interesting potential of antioxidant, antimicrobial, antifungal, antiobesity and lipid metabolism, cytotoxicity, antiinflammatory, antimalarial and antinicotine stress activities of G. atroviridis. This article discusses on G. atroviridis in aspect of its chemical constituents and bioactivities; in vitro and in vivo as well the clinical study made on this plant despite the limited data available. It is also an effort to update G. atroviridis data on its phytochemical and pharmacological data of the plant in the recent 15 years.

Garcinia atroviridis’in fitokimyasal ve farmakolojik özellikleri

Garcinia atroviridis ya da yerel adıyla ‘Asam Gelugur’ ekşi tadı nedeniyle lezzet verici olarak kullanılmaktadır. Bu özelliğinin yanında G.atroviridis, geleneksel tedavide de insan sağlığına olumlu etkileri nedeniyle kullanılmaktadır. Yapılan araştırmalarda, bitkinin; antioksidan, antimikrobiyel, antifungal, anti-obezite ve lipid metabolizması düzenleyici, antienflamatuvar, antimalariyal, nikotin stresini ortadan kaldırıcı ve sitotoksik özellikleri çalışılmıştır. Bu makale kapsamında G.atroviridis’in içerdiği kimyasal bileşenler ve biyolojik özellikleri incelenmiş, in vitro ve in vivo çalışmalara ek olarak sınırlı sayıdaki klinik çalışma hakkında da bilgi verilmiştir. Bu çalışmada, son 15 yılda G.atroviridis’in fitokimyasal ve farmakolojik özellikleri ile ilgili yapılan araştırmaların derlenmesi ile G.atroviridis hakkında güncel bir kaynak oluşturulması amaçlanmıştır.

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