Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

The antibacterial, antifungal and antimycobacterial effects of ethanolic extracts obtained from aerial parts and roots of five Vincetoxicum taxa (V. canescens subsp. canescens, V. canescens subsp. pedunculata,V. parviflorum, V. fuscatum subsp. fuscatum and V. fuscatum subsp. boissieri) were tested against two Gram (+) bacterial strains (Staphylococcus aureusandBacillus subtilis), three Gram (-) bacterial strains (Escherichia coli, Acinetobacterbaumanniiand Aeromonashydrophila),three fungal strains (Candida glabrata, Candida parapsilosis andCandida tropicalis) and Mycobacterium tuberculosisby using thebroth dilution method. Ethambutol, Isoniazid, Ampicillin and Fluconazole were used as reference antimicrobial agents. All tested extracts showed significant antibacterial activity against A.baumanniiwith MIC values ranging from 31.25 to 62.5 μg/ml when compared to reference drug Ampicillin with 125 μg/ml MIC value. Moreover, the extracts obtained from aerial parts of V. fuscatum subsp. boissieriand roots ofV. canescens subsp. pedunculata were found the most effective extracts against A.baumanniiwith 31.25 μg/ml MIC value.

___

[1]Ngezahayo J, Ribeiro SO, Fontaine V, Hari L, Stévigny C, Duez P. In vitrostudy of five herbs used against microbial infections in Burundi. Phytother Res. 2017; 31(10): 1571-1578.

[2]Shamsizadeh Z, Nikaeen M, Esfahani BN, Mirhoseini SH, Hatamzadeh M, Hassanzadeh A. Detection of antibiotic resistant Acinetobacter baumanniiin various hospital environments: potential sources for transmission of Acinetobacter infections. Environ Health Prev Med.2017; 22(44): 1-7.

[3]Pașca C, MàrghitaşL, Dezmirean D, BobişO, Bonta V, ChirilàF, Matei I, FiţN. Medicinal plants based products tested on pathogens isolatedfrom Mastitis Milk. Molecules. 2017; 22(9): 1473-1489.

[4]Uma K, Xin H, Kumar BA. Antifungal effect of plant extract and essential oil. Chin J Integr Med. 2017; 23(3): 233-239.

[5]Ayoub IM, El-Shazly M, Lu MC, Singab ANB. Antimicrobial and cytotoxic activities of the crude extracts of Dietes bicolorleaves, flowersand rhizomes. S Afr J Bot. 2014; 95: 97-101.

[6]Siddiqui W, Sharangi AB, Singh JP, Thakur PK, Ayala-Zavala JF, Singh A, Dhua RS. Antimicrobial properties of teas and their extracts in vitro. Crit Rev Food Sci Nutr.2016; 56(9): 1428-1439.

[7]DiTommaso A, Lawlor FM, Darbyshire SJ. The biology of invasive alien plants in Canada 2. Cynanchum rossicum(Kleopow) Borhidi (=Vincetoxicum rossicum(Kleopow) Barbar.) and Cynanchum louseae(L.) Kartesz&Gandhi (= Vincetoxicum nigrum(L.) Moench). Can J Plant Sci. 2004; 85(1): 243-263.

[8]Heywood VH, Brummitt RK, Culham A, Seberg O. Flowering Plant Families of the World. Firefly Books, Oxford University Press, New York, USA 2007.

[9]Liede S. Cynanchum-Rhodostegiella-Vincetoxicum-Tylophora (Asclepiadaceae): New considerations on an old problem. Taxon. 1996; 45(2): 193-211.

[10]Leimu R. Variation in the mating system of Vincetoxicum hirundinaria (Asclepiadaceae) in peripherial island populations. Ann Bot. 2004; 93(1): 107-113.

[11]Sliumpaite I, Murkovic M, Zeb A, Venskutonisa PR. Antioxidant properties and phenoliccomposition of swallow-wort (Vincetoxicum luteaL.) leaves. Ind Crops Prod.2013; 45: 74-82.

[12]Mansoor A, Ibrahim MA, Zaidi MA, Ahmed M. Antiprotozoal activities of Vincetoxicum stocksiiand Carum copticum.Bangladesh J Pharmacol.2011; 6(1): 51-54.

[13]Lavault M, Richomme P, Bruneton J. Acetophenones and new pregnane glycosides from the roots of Vincetoxicum hirundinaria. Fitoterapia. 1999; 70(2): 216-220.

[14]Pavela R. Antifeedant activity of plant extracts on Leptinotarsa decemlineataSay. and Spodoptera littoralisBois. larvae. Ind Crops Prod. 2010; 32(3): 213-219.

[15]Nowak R, Kisiel W. Hancokinol fromVincetoxicum officinale. Fitoterapia. 2000; 71(5): 584-586.

[16]Lavault M, Richomme P, Bruneton J. New phenanthroindolizidine N-oxides alkaloids isolated from Vincetoxicum hirundinariaMedic. Pharm Acta Helv. 1994; 68(4): 225-227.

[17]Coassini-Lokar L, Poldini L. Herbal remedies in the traditional medicine of the Venezia Giulia Region (North East Italy).J Ethnopharmacol.1988;22(3):231-279.

[18]Baytop T. Türkiye'de Bitkiler ile Tedavi Geçmişte ve Bugün. İlaveli 2. Baskı, İstanbul Üniversitesi Eczacılık Fakültesi, Nobel Tıp Kitap Evleri, İstanbul, Türkiye 1984.

[19]Altundağ E, Öztürk M. Ethnomedicinal studies on the plant resources of east Anatolia, Turkey. Procedia Soc Behav Sci. 2011; 19: 756-777.

[20]Tuzlacı E, Doğan A. Turkish folk medicinal plants, IX: Ovacık (Tunceli). Marmara Pharm J. 2010; 3(14): 136-143.

[21]Mogg C, Petit P, Cappuccino N, Durst T, McKague C, Foster M, Yack JE, Arnason JT, Smith ML. Test of the antibiotic properties of the invasive vine Vincetoxicum rossicum against bacteria, fungi and insects. Biochem Syst Ecol. 2008; 36(5-6): 383-391.

[22]Gibson DM, Krasnoff SB, Biazzo J, Milbrath L. Phytotoxicity of antofine from invasive Swallow-Worts. J Chem Ecol. 2011; 37(8): 871-879.

[23]Zaidi MA, Crow JSA. Biologically active traditional medicinal herbs from Balochistan, Pakistan. J Ethnopharmacol. 2005; 96(1-2): 331-334.

[24]Staerk D, Christensen J, Lemmich E, Duus J, Olsen CE, Jaroszewski JW. Cytotoxic activity of some phenanthroindolizidine N-Oxide alkaloids from Cynanchum vincetoxicum. J Nat Prod. 2000; 63(11): 1584-1586.

[25]Staerk D, Lykkeberg AL, Christensen J, Budnik BA, Abe F, Jaroszewski JW. In vitrocytotoxic activity of phenantroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells. J Nat Prod. 2002; 65(9): 1299-1302.

[26]Pavela R, Sajfrtova M, Sovova H, Barnet M, Karban J. The insecticidalactivity of Tanacetum parthenium (L.) Schultz Bip. extracts obrained by supercritical fluid extraction and hydrodistillation.Ind Crops Prod. 2010; 31(3): 449-454.

[27]Güzel S, Pavela R, Kökdil G. Phytochemistry and antifeedant activity of root extracts from some Vincetoxicumtaxa against Leptinotarsa decemlineataand Spodoptera littoralis. JBiopest.2015; 8(2): 128-140.

[28]Güzel S, Pavela R, İlçim A, Kökdil G. Phytochemical composition and antifeedant activity of five Vincetoxicum taxa against Spodoptera littoralisand Leptinotarsa decemlineata. Marmara Pharm J. 2017; 21(4): 872-880.

[29]Stöckel K, Stöcklin W, Reichstein T. Die glucoside von Vincetoxicum hirundinariaMEDIKUS. 1. Mitteilung: Isolierung und Spaltprodukte. Glucoside und Aglucon. 316 Mitteilung. Helv Chim Acta. 1969; 52(5): 1175-1202.

[30]Tanker N, Koyuncu M, Coşkun M. Farmasotik Botanik,Ankara Universitesi Eczacılık Fakültesi, Ankara, Türkiye 2004.

[31]Browicz K. Vincetoxicum N.M. Wolf. In: Davis PH (Ed), Flora of Turkey and the East Aegean Islands. Edinburgh, 1978, 6. pp. 163-173.

[32]Güzel S, Pavela R, Kökdil G. Evaluation of antifungal effect of different polarity extracts from five Vincetoxicumtaxa against Aspergillus fumigatus.International Anatolian Academic Online Journal/Health Science. 2015; 3(2): 1-9.

[33]Erşen D, Ülger M, Mangelinckx S, Gemili M, Şahin E, Nural Y. Synthesis and anti(myco)bacterial activity of novel 5,5-diphenylpyrrolidine N-aroylthiourea derivatives and a functionalized hexahydro-1H-pyrrolo[1,2-c]imidazole.Med Chem Res.2017; 26(9): 2152-2160.

[34]NCCLS. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard-Second Edition. NCCLS document M27-A2 (ISBN 1-56238-469-4). NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA 2002.

[35]Sönmez M, Çelebi M, Berber I. Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. Eur J Med Chem.2010; 45(5): 1935-1940.

[36]Güzeldemirci NU, Küçükbasmacı Ö. Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety. Eur J Med Chem.2010; 45(1): 63-68.

[37]Nateche F, Martin A, Baraka S, Palomino JC, Khaled S, Portaels F. Application of the resazurin microtitre assay for detection of multidrug resistance in Mycobacterium tuberculosisin Algiers. J Med Microbiol.2006; 55: 857-860.

[38]Arif T, Mandal TK, Dabur R. 9. Natural products: Anti-fungal agents derived from plants. In: Mishra BB (Ed) Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry. Research Signpost, Kerala, 2011, pp. 283-311.

[39]Cowan MM. Plant productsas antimicrobial agents. Clin Microbiol Rev. 1999; 12(4): 564-582.

[40]Bajpai VK. Antimicrobial bioactive compounds from marine algae: A mini review. IndianJ Geomarine Sci.2016; 45(9): 1076-1085.

[41]Kowalczyk D, Świeca M, Cichocka J, Gawlik-Dziki U. The phenolic content and antioxidant activity of the aqueous and hydroalcoholic extracts of hops and their pellets. J Inst Brew.2013; 119(3): 103-110.

[42]Bazzaz F, Haririzadeh G. Screening of Iranian plants for antimicrobial activity. Pharm Biol.2003; 41(8): 573-583.

[43]Pirbalouti AG, Jahanbazı P, Enteshari S, Malekpoor F, Hamedi B. Antimicrobial activity of some Iranian medicinal plants. Arch Biol Sci.2010; 62(3): 633-642.

[44]Alimpić A, Knežević A, Milutinović M, Stević T, Šavikin K, Stajić M, Marković S, Marin P, Matevski V, Duletić-Laušević S. Biological activities and chemical composition of Salvia amplexicaulisLam. extracts. Ind Crops Prod. 2017; 105: 1-9.

[45]Lean SS, Yeo CC. Small, enigmatic plasmids of the nosocomial pathogen, Acinetobacter baumannii: good, bad, who knows? Front Microbiol. 2017; 8: 1547-1555.

[46]CLSI. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That GrowAerobically; Approved Standard-Ninth Edition.CLSI document M07-A9. Wayne, PA: Clinical and Laboratory Standards Institute 2012.
Marmara Pharmaceutical Journal-Cover
  • ISSN: 1309-0801
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1985
  • Yayıncı: Marmara Üniversitesi
Sayıdaki Diğer Makaleler

Quantum-chemical free energy calculation of vinpocetine molecule release from sodium alginate

Yulia POLKOVNIKOVA, Halahakoon Amila JEEWANTHA, Kseniya KORYANOVA

Effects of GPER-1 receptor activation on the reactivity of pulmonary vascular bed and its possible protective role on ischemia /reperfusion

Gökçen TELLİ, Banu Cahide TEL, Bülent GÜMÜŞEL, Kansu BÜYÜKAFSAR

Evaluation of avocado (Persea americanaMill.) leaves in terms of public health

Gülsen KENDİR, Ayşegül KÖROĞLU

Analysis of anticancer drugs using thin layer chromatography–A review

Duygu UĞUR YENİCELİ, Alper UĞUR

Cardioprotective effects of Hypericum triquetrifoliumTurra. against cyclophosphamide related cardiotoxicity in rats

Songül ÇETİK YILDIZ, Cumali KESKİN, Varol ŞAHİNTÜRK, Adnan AYHANCI

Biological activity studies on the aqueous methanol extract of Anchusa undulataL. subsp. hybrida (Ten.) Coutinho

Kevser TABAN, Nuraniye ERUYGUR, Osman ÜSTÜN

The protective effect of spironolactone and role of the Na+/K+-ATPase pump on intestinal ischemia/reperfusion injury

Cebrail AKYÜZ, Orhan UZUN, Oguzhan SUNAMAK, Ayliz VELİOĞLU-ÖĞÜNÇ, Şule ÇETİNEL, Ahmet ÖZER ŞEHİRLİ

Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

SEVDA GÜZEL, Gamze KÖKDİL, Mahmut ÜLGER, Gönül ASLAN

Hydroalcoholic extract of Zataria multifloramitigates cisplatin-induced oxidative stress, apoptosis and hepatotoxicity in mice

Shokooh KARIMI, Seyed Jalal HOSSEINIMEHR, Hamid Reza MOHAMMADI, Ali Reza KHALATBARY, Fereshteh TALEBPOUR AMIRI

Licorice cream promotes full-thickness wound healing in Guinea pigs

Nafise HANAFI, Fereshteh TALEBPOURAMIRI, Somayeh SHAHANI, Reza ENAYATIFARD, Maryam GHASEMI, Abbas Ali KARIMPOUR