Yavuz KARABAĞ, Bahattin BALCI, Yüksel KAYA

Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Ekokardiyografik Sağ Ventrikül Deformasyon Parametrelerinin Değerlendirilmesi

Giriş: Çalışmamızda klinik sağ ventrikül (SV) yetersizlik bulguları olmayan kronik obstrüktif akciğer hastalığı (KOAH)’na sahip hastaları sağlıklı bireylerle karşılaştırarak istirahatte SV geometrisi ve fonksiyolarını iki boyutlu speckle-tracking kullanarak değerlendirmeyi amaçladık. Hastalar ve Yöntem: Çalışma popülasyonunu, Kafkas Üniversitesi Gögüs Hastalıkları Kliniğinde 2014 yılında ayaktan takip edilen daha öncesinde KOAH tanısı olup klinik SV yetmezliği bulgusu olmayan 28 hasta ve benzer demografik özellikler taşıyan 24 sağlıklı birey oluşturmuştur. Bulgular: Konvansiyonel ekokardiyografik özelliklerinden ortalama pulmoner arter basıncı, SV serbest duvar kalınlığı ve SV serbest duvar strain parametreleri haricindeki parametreler gruplar arasında benzerdi. KOAH grubunda SV serbest duvar strain parametrelerinden; SV serbest duvar bazal, mid ve apikal strain değerleri kontrol grubuna kıyasla daha düşük saptandı (her karşılaştırma için p< 0.05 idi). Ortalama pulmoner arter basıncı ve sırası ile SV serbest duvar bazal, mid ve apikal strain değerleri arasında istatistiksel olarak anlamlı negatif korelasyon izlendi. Sonuç: Çalışmamızın sonucuna göre KOAH hastalarında olan SV disfonksiyonunu SV strain parametrelerinin konvansiyonel ekokardiyografik yöntemlerden daha erken tespit ettiğini saptadık.

Anahtar Kelimeler:

Kronik obstrüktif akciğer hastalığı, sağ ventrikül disfonksiyonu, ekokardiyografi, strain, strain rate

Evaluation of Echocardiographic Right Ventricular Deformation Parameters in Patients with Chronic Obstructive Pulmonary Disease

Introduction: This study aimed to evaluate patients with chronic obstructive pulmonary disease (COPD) who did not have clinical signs of right ventricular (RV) failure using two-dimensional speckle-tracking of RV geometry and functions at rest in comparison to healthy subjects.Patients and Methods: The study population comprised 28 patients with COPD and 24 healthy subjects with similar demographic characteristics who were followed up at the Department of Chest Diseases of Kafkas University in 2014.Results: Conventional echocardiographic parameters, except for mean pulmonary artery pressure, RV free wall thickness, and RV free wall strain parameters, were similar between the groups. RV free wall strain parameters in the COPD group, including RV free wall basal, mid, and apical strain values, were significantly lower than those in the control group (p< 0.05 for each comparison). A statistically significant negative correlation was observed between the mean pulmonary artery pressure and the RV free wall basal, mid, and apical strain values. Conclusion: We concluded that RV strain parameters may be superior to conventional echocardiographic methods for assessing RV dysfunction prior to clinically evident RV failure.

Keywords:

Chronic obstructive pulmonary disease, right ventricular dysfunction, echocardiography, strain, strain rate,

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi