Rabia DEMİRTAŞ, Şenay Erdoğan DURMUŞ, Enver YARIKKAYA

TÜRKİYE’DE KUZEY-DOĞU ANADOLU BÖLGESİNDEKİ MİDE BİYOPSİLERİNİN İNCELENMESİ İLE: MORFOLOJİK-KLİNİK UYUMUN ÖNEMİ

AMAÇ: Çalışmamızda Türkiye'deki Kuzey-Doğu Anadolu

Anahtar Kelimeler:

Gastrik biyopsiler, Malignite, Biyopsi tekrarı

THE IMPORTANCE OF MORPHOLOGICAL-CLINICAL CONSISTENCY: THROUGH THE REVIEW OF GASTRIC BIOPSIES IN NORTH-EASTERN ANATOLIA REGION IN TURKEY

OBJECTIVE: In our study we aimed to make a generallyreview of gastric biyopsies in North-Eastern Anatoliaregion in Turkey such as; percentages of malignancy ordysplasia, reasons of re-biopsy recommendations andresults of second biopsies if taken.MATERIAL AND METHODS: 1840 gastric biopsies whichexamined by 3 pathologists at 2 centers were analyzedretrospectively. Percentages of malignancy or dysplasia,cases which were recommended for re-biopsies, reasonsof recommendations and results of re-biopsies wereexamined. In the results of the second biopsies, dysplasia,malignancy and gastritis were accepted as a significantresult.RESULTS: The mean age of our cases was 52.9 ± 16.6 years(range: 18-95 years). 1012 (55%) patients were femalesand 828 (45%) patients were males. In 90 out of 1840cases, biopsies were taken for suspect of malignancy,clinically. 35 of 90 cases were reported as malignancy. In61 out of 1840 cases re-biopsy were recommended. Reasonsof recommendations for re-biopsy categorized inthree groups: suspect of malignancy- clinically, suspectof malignancy- morphologically, insufficient (superficial)biopsies. 12 (46.2%) of 26 cases which were taken secondbiopsies were reported as malignancy and gastricdysplasia. Only in 2 (7.6%) of 26 cases the results wereinsignificant (insufficient biopsy).CONCLUSIONS: Endoscopic findings provide informationabout the diagnosis but are not pathognomonicwhich also need histological confirmation. Closeworking relationship and a good dialogue between thepathologist and the gastroenterologist is essential forclinical-morpological consistency, morphological-clinicalconsistency and final diagnosis.

Keywords:

Gastric biopsies, Malignancy, biopsies,

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1. Niknam R, Manafi A, Fattahi MR, Mahmoudi L. The association between gastric endoscopic findings and histologic premalignant lesions in the Iranian rural population. Medicine (Baltimore) 2015;94: e715.
2. Fock KM. Review article: the epidemiology and prevention of gastric cancer. Aliment Pharmacol Ther 2014;40:250–260.
3. Yuyucu Karabulut Y, Bozdoğan Arpaci R, Dölek Y, Topal F. What is the consistency between the diagnoses of endoscopists and pathologists concerning malignant lesions of the gastrointestinal tract? Endoscopy Gastrointestinal 2014;22:53- 6.
4. Al Hamdani A, Fayadh HM, Abdul Majeed BA. Helicobacter pylori gastritis: correlation between endoscopic and histological findings. IJGE 2001;1:43-8.
5. Kasap E, Güngör G, Aygör E, et al. What is the consistency between the diagnoses of endoscopists and pathologists concerning gastroduodenal mucosa? Endoscopy 2012;20:13-6.
6. Irkorucu O, Gultekin FA, Ucan BH, et al. Agreement Between Pathologic Diagnosis and Endoscopic Findings on Esophagogastroduodenoscopy Performed by General Surgeons. Med Bull Haseki 2011;49:26–9.
7. Sharma S, Makaju R, Dhakal R, et al. Correlation between Endoscopic and Histopathological Findings in Gastric Lesions. Kathmandu Univ Med 2015;51:216-9.
8. Pailoor K, Sarpangala MK. Histopathological diagnosis of gastric biopsies in correlation with endoscopy- A study in a tertiary care center. Adv Lab Med Int 2012;3:22-31.
9. Redeen S, Petersson F, Jonsson KA, Borch K. Relationship of gastroscopic features to histological findings in gastritis and Helicobacter pylori infection in a general population sample. Endoscopy 2003;35:946–50.
10. Eshmuratov A, Nah JC, Kim N, et al. The correlation of endoscopic and histological diagnosis of gastric atrophy. Dig
11. Lim JH, Kim N, Lee HS, et al. Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia. Gut Liver 2013;7:41–50.
12. Carr NJ, Leadbetter H, Marriott A. Correlation between the endoscopic and histologic diagnosis of gastritis. Ann Diagn Pathol 2012;16:13–5.
13. Sheiko MA, Feinstein JA, Capocelli KE, Kramer RE. The concordance of endoscopic and histologic findings of 1000 pediatric EGDs. Gastrointest Endosc 2015;81:1385-91.