Yutma Güçlüğünün Nadir Bir Nedeni Eozinofilik Özofajit: İki Olgu Sunumu ve Literatür Derlemesi

Eozinofilik özofajit (EÖ) özofagusun kronik, immün aracılı bir hastalığıdır ve genellikle özofageal disfonksiyon, retrosternal yanma, ve eozinofil baskın inflamasyon ile karakterizedir. EÖ’li birçok hasta çoğunlukla yutma güçlüğü, reflü benzeri şikayetler ve yutma güçlüğü ile prezente olur. Her ne kadar diyetsel alerjenler patofizyolojide çoğunlukla suçlansa da bilinmeyen birçok faktörün de patofizyolojiden sorumlu olduğuna inanılmaktadır. Biz bu vaka raporlarında kliniğimize yutma güçlüğü ile başvuran ve EÖ tanısı alan 2 hastayı sunmayı amaçladık. Tedavide oral flutikazon ve diyet kısıtlaması her iki hastaya da başlandı ve izlem sürecinde her iki hastada başarılı sonuçlar elde edildi.

Eosinophilic Esophagitis as a Rare Cause of Dysphagia: Two Case Presentation with Literature Review

Eosinophilic esophagitis (EO) is a chronic, immune mediateddisease of esophagus characterized with esophagealdysfunction, retrosternal heartburn, and eosinophilpredominantinflammation. Most patients with EO clinicallypresents with dysphagia, reflux-like symptoms and swallowingdifficulties. Although food allergens are mostly accused in thepathophysiology of EO, there is still unknown additionalfactors that are belived to be exist in the pathophysiology.Herein, we would like to present two patients who admitted toour clinic with the complaint of dysphagia and was diagnosedas EO. Oral fluticazone treatment was started with dietaryrestriction to both patients. A favorable outcome was achievedduring follow-up.

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