Havva Belma KOÇER, Yusuf ARSLAN, Yeşim AKDENİZ, Ali İmran KÜÇÜK

Vitamin D Düzeylerinin Tiroidektomi Sonrası Gelişen Hipokalsemi Üzerine Etkisi

GİRİŞ ve AMAÇ: Bu çalışmada preoperatif olarak ölçülen D vitamini düzeylerinin postoperatif olarak gelişen hipokalsemiler üzerine etkisi araştırılmıştır YÖNTEM ve GEREÇLER: Araştırmamıza 2015 yılı ocak ayı ile 2016 yılı Mart ayı arasında Sakarya Üniversitesi Eğitim ve Araştırma Hastanesi Genel Cerrahi Kliniğinde benign, malign ya da tirotoksikoz nedeni ile opere edilen ve preoperatif olarak D vitamini düzeyi bakılmış 106 hasta retrospektif olarak dahil edilmiştir. BULGULAR: Hastaların yaş ortalaması 50,6dır (min: 19 max: 82). Hastaların 94’ü kadın 12’si ise erkektir. Tiroidektomi yapılan hastaların preoperatif vitamin D düzeyleri değerlendirildiğinde %81,1’inde (n: 86) yetmezlik (30 ng/dl) olduğu görülmüştür. Postoperatif hastaların %18,9’unda geçici hipokalsemi semptomları gelişmiş olup, hastalar kalsiyum (Ca) tedavisi almıştır. Hipokalsemi semptomlarının oluşmasına etki eden faktörler incelendiğinde; yaş, hipertiroidi, tiroidit, paratiroid bezinin çıkartılması ve operasyon tipinin postoperatif hipokalsemi semptom varlığını etkilemez iken,

Effect of Vitamin D Level on Post-Thyroidectomy Hypocalcemia

INTRODUCTION: In this study, the effect of preoperativevitamin D levels on postoperative hypocalcemia wasinvestigated.METHODS: We retrospectively investigated 106 patients whowere operated for benign – malign thyroid nodules orthyrotoxicosis and whose preoperative vitamin D levels weremeasured in the General Surgery Clinic of Sakarya UniversityEducation and Reserch Hospital between January 2015 andMarch 2016.RESULTS: The average age of the patients is 50,6 (min: 19,max: 82). There were 94 female and 12 male patients. Whenthe vitamin D levels of the patients undergoing thyroidectomywere evoluated, it was found that 59,8% (n: 63) deficient,20,8% (n: 22) insufficient (30 ng/dl). Transient hypocalcemia symptomsdeveloped in 18,9% of the postoperative patients and thepatients had received calcium (Ca) therapy. When factorsaffecting the occurence of hypocalcemia symptoms wereexamined, it was seen that age, hyperthyroidism, thyroiditis,parathyroid gland removal and operation type did not affectthe postoperative hypocalcemia symptom status; however,patients with vitamin D below 30 ng/dl had more hypocalcemia23,3% & 0%)(p: 0,017).DISCUSSION and CONCLUSION: As suggested by ourstudy and other studies, preoperative vitamin D levels shouldbe assested in every patient who will undergo thyroidectomyand vitamin D replacement should be performed in everypatient who has insufficiency..

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