Superior Semisirküler Kanal Dehissansında Distorsiyon Ürünü Otoakustik Emisyon Ölçüm Değerlerinin Araştırılması
GİRİŞ ve AMAÇ: Süperior semisirküler kanal dehissansı vertigo ile başvuran hastalarda saptanabilen bir hastalıktır. Klinikte vertigo, otofoni, iletim tipi işitme kaybı, nistagmus saptanabilir. Otoakustik emisyon dış tüylü hücrelerin aktivitesine bağlı oluşan, koklea fonksiyonunun monitörizasyonunda kullanılan non-invaziv bir testtir. Biz çalışmamızda superior semisirküler kanal dehissansı olan hastalarda otoakustik emisyon değerlerini araştırdık. YÖNTEM ve GEREÇLER: Hastalar iki gruba ayrıldı. Tek taraf dehissans olan hastaların test kulakları (1.grup), karşı sağlam kulaklar ile, bilateral dehissans olan hastaların kulakları (2.grup), kontrol grubunun (3. grup) aynı taraf kulakları ile distorsiyon product ve sinyal-gürültü oranı ölçümleri yapılarak karşılaştırıldı. BULGULAR: Distorsiyon ürünü otoakustik emisyon ölçümü sonrası amplitüd değerleri ve sinyal gürültü oranı değerleri esas alınarak, 1-8 kHz’ de değerler karşılaştırıldı. Tek taraf dehissans olan olgularda, karşı sağlam kulak ile test kulağı karşılaştırıldığında amplitüd ve sinyal-gürültü oranı değerlerinin test kulağında, sırasıyla 1 ve 6 kHz’de anlamlı olarak düştüğü saptandı (p
Investigation of Distortion Product Otoacoustic Emission Values in Superior Semicircular Canal Dehiscence
INTRODUCTION: Superior semicircular canal dehiscencehas been found in patients with vertigo symptoms. Patients mayhave otophonia, conductive hearing loss, nistagmus withvertigo. Otoacustic emission is a non-invasive test used formonitoring cochlea function due to outer hair cell activity. Inour study we investigated otoacustic emission results insuperior semicircular canal dehiscence patients.METHODS: Patients were divided into two groups. Patientswith unilateral superior semicircular canal dehiscence werecompared with the opposite normal side of their ear, usingdistortion product and signal-noise ratio values at 1-8 kHz.Patients with bilateral semisircular canal dehiscence werecompared with control group patient’s ears.RESULTS: Distorsion product otoacustic emissionmeasurements and signal noise ratio values were significantlydecreased at 1 kHz and 6 kHz in unilateral patientsrespectively(p
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- Minor LB, Solomon D, Zurich JS, et al. Sound
and/or pressure induced vertigo due to bone
dehiscence of the superior semicircular canal. Arch
Otolaryngol Head Neck Surg 1998; 124: 249-58.
- Krombach GA, Di Martino E, Schmitz RT, et
al. Posterior semicircular canal dehiscence: a
morphological cause of vertigo similar to superior
semicircular canal dehiscence. Eur Radiol 2003; 13 :
1444-50.
- Belden CJ, Weg N, Minor LB, et al. CT
evaluation of bone dehiscence of the superior
semicircular canal as a cause of sound and/or
pressure induced vertigo. Radiology 2003; 226 :
337-43.
- Hillman TA, Kertesz TR, Hadley K. Reversible
peripheral vestibulopathy: The treatment of superior
semicircular canal dehiscence. Otolaryngol Head
Neck Surg 2006; 134: 431-439.
- Hirvonen TP, Carey JP, Liang CJ. Superior
canal dehiscence: Mechanism of pressure sensitivity
in a chinchilla model. Arch Otolaryngology Head
Neck Surgery 2001; 127 :1331-36.
- Brantberg K, Bergenius J, Mendel L, et al.
Symptoms findings and treatment in patients with
dehiscence of the superior semicircular canal. Acta
Otolaryngol 2001; 121: 6875.
- Kileny PR, Zwolan TA. Diagnostic and
rehabilitative audiology. In: Cummings CW, editors.
Otolaryngol Head Neck Surg, vol.4.3rd ed. St Louis
(Mo): Mosby-Year Book; 1998: 2875-93.
- Carey JP, Minor LB, Nager GT. Dehiscence or
thinning of bone overlying the superior semicircular
canal in a temporal bone survey. Arch Otolaryngol
Head Neck Surg 2000; 126: 137-47.
- Teixido MT, Gregory JA, Kung BC. Clinical
experience with symptomatic superior canal
dehiscence in a single neurotologic practice.
Otolaryngoly Head Neck Surg 2008; 139: 405-413.
- Venema HW, Phoa SSKS, Mirck PGB.
Petrosal bone: coronal reconstructions from axial
spiral CT data otained with 0.5 mm collimation can
replace direct coronal sequental CT scans. Radiology
1999; 213: 375 -82.
- Minor LB. Superior canal dehiscence
syndrome. Am J Otol 2000; 21 :9-19.
- Mikulec A, Mc Kenna J, Ramsey J. Superior
semicircular canal dehiscence presenting as
conductive hearing loss without vertigo. Otology
Neurotology 2004; 25:121-129.
- AwST , Todd MJ , AwGE. Click evoked
vestibuloocular reflex: stimulus response properties
in superior canal dehiscence. Neurology 2006; 66:
1079-1087.
- Hırvonen TP, Weg N, Zınreıch J, et al. Hıgh
resolution CT findings suggest a devolopmental
abnormality underlying superior canal dehiscence
syndrome. Acta Otolaryngol 2003; 123: 477-481.
- Govvaerts PJ, Casselman j, Daemers K, et al.
Audiological findings in large vistibular aqueduct
syndrome. İnt J Pediatr Otorhinolaryngol 1999; 51
:157-64.
- Modugno G,Brandolini C,Savastio G,et al.
Superior semicircular canal dehiscence: a series of
13 cases.ORL J Otorhinolaryngol Relat Spec 2005;
67: 180-4.
- Minor LB, Carey JP, Cremer PD, et al.
Dehiscence of bone overlying the superior canal as a
cause of apparent conductive hearing loss. Otol L
Neurotol 2003 ; 24:270-8.
- Chien W, Ravicz ME, Merchant SN, et al.
Measurements of human middle and inner ear
mechanics with dehiscence of the superior
semicircular canal. Otol Neurotol 2007 ; 28 : 250-7.
- Rosowski JJ, Songer JE, Nakajima HH, et al.
Clinical experimental and theoretical investigations
of the effect of superior semicircular canal
dehiscence on hearing mechanisms. Otol Neurotol
2004; 25: 323-32.
- Watson SR, Halmagyi GM, Colebatch JG.
Vestibular hypersensitivity to sound: structural and
functional assesment. Neurology 2000 ; 54 : 722-
728.
- M Cox K, Lee DJ, Carey JP, et al. Dehiscence
of bone overlying the superior semicircular canal as
a cause of an air-bone gap on audiometry: A case
study. American Journal of Audiology 2003; 12 : 11-
16.
- Lonsburry- Martin BL, Harris FP, Stanger BB,
et al. Distortion product otoacustic emissions in
humans. I.Basis Properties in Normally Hearing
Subjects. Ann Otol Rhinol Laryngol 1990; 147: 3-
13.
- Sakamato M, Kanga K, Kamio T. Extended
hıgh-frequency ototoxicity induced by the first
administration of cisplatin. Otolaryngol Head Neck
Surg 2000; 122 (6): 828-833.
- Campell KCM, Durrant J. Audiological
monitoring for ototoxicity. The Otolaryngologic
Clinics of North America 1993, 26(5): 903-917.
- Thabet EM. Transient evoked otoacoustic
emissions in superior canal dehiscence syndrome.
Eur Arch Otorhinolaryngol 2011;268:137-141.
- Khovels R, Freeman S, Sohmer H. Transient
Evoked Otoacustic Emissions can be recorded in the
rats. Hearing Research 1996; 97: 120-126.
- Moulin A, Bera JC, Collet L. Distortion
product otoacustic emissions and sensorineural
hearing loss. Audiology 1994 ; 33 : 305-326.
- Nakamura M, Yamasoba T, Kaga K. Changes
in otoacustic emissions in patient with idiopathic
sudden deafness. Audiology 1997 ; 36 : 121-135.
- Merchant SN, Rosowski JJ. Conductive
hearing loss caused by third window lesions of the
inner ear. Otology Neurotology 2008; 29: 282-289.
- Schmuziger N, Allum J, Buitrago-Tellez C, et
al. İncapacitating hyphersensitivity to ones own
body sounds due to a dehiscence of bone overlying
the superior semicircular canal. A case report. Eur
Arch Otorhinolaryngol 2006 ; 263 : 69-74.