Mehmet Zülküf AKDAĞ, İbrahim KAPLAN, Mustafa Salih ÇELİK, Mehmet Cihan YAVAŞ

Serum Paraoksonaz (PON1) Üzerine Elektromanyetik Alanların Etkisinin Araştırılması

GİRİŞ ve AMAÇ: Toplumda elektrikli cihazların yaygınolarak kullanılması ve bu cihazlarla yakın temas halindeolması hem endişeye hem de halk sağlığını etkilemektedir. Buçalışmanın amacı, farklı günlerde yüksek gerilim kaynaklıelektromanyetik alan maruziyetinin, sıçanların serumparaoksanaz 1 aktivitesini etkileyip etkilemediğiniaraştırmaktır. YÖNTEM ve GEREÇLER: Bu retrospektif çalışmada, Mart2008-Nisan 2018 tarihleri arasında İstanbul Bakırköy Dr. SadiKonuk Eğitim ve Araştırma Hastanesi'nde abdominal duvarendometriozisi tanısı alan hastaların bilgisayar tabanlı tıbbikayıtları incelendi ve analiz edildi. BULGULAR: Yirmi altı ve elli iki günlük yüksek gerilimmaruziyet grubunda paraoksonaz (PON1) aktivitesinde kontrolgrubuna göre bir azalma bulduk. Gruplar arasında iseistatistiksel olarak önemli (p

Investigation of The Effects of Electromagnetic Fields on SerumParaoxonase (PON1)

INTRODUCTION: The widespread use of electrical devices inthe society and being in close contact with these devices causeboth anxiety and affect public health. The aim of this study is toinvestigate whether high voltage induced electromagnetic fieldexposure on different days affects serum paraoxanase 1activity of rats. METHODS: The study included 24 adult male wistar albinorats, weighing 320 grams on average. They were randomlygrouped into 3 as n: 8. Group 1: Sham-control, Group 2: 26days High voltage (HV) and Group 3: 52 days HV. The rats inthe 26-day and 52-day experimental groups (Groups I, II)received electric and magnetic fields for 8 hours each day. RESULTS: We found a decrease in paraoxonase (PON1)activity in the 26- and 52-day high-voltage exposure groupcompared to the control group. A statistically significant(p=0.000) change was found between the groups. DISCUSSION AND CONCLUSION: :Our study suggests thatthe exposure to high voltage line may cause a reduction ofparaoxonase 1 activity. We've noticed that short-termexposures, compared to long-term ones, may lead to lowerparaoxonase 1 activity. Therefore, our study also points to theimportance of further research in this regard.

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