Yiğit ÇANGA, Mehmet Baran KARATAŞ, Dilaver ÖZ, Mehmet ZENGİN, Özge GÜZELBURÇ, Nizamettin S, Ayşe EMRE

Nötrofil-Lenfosit Oranı Mitral Kapak Çökmesi Olan Hastalarda Akut Göğüs Ağrısı İle İlişkilidir

ÖZGİRİŞ ve AMAÇ: : Mitral kapak çökmesi (MVP) tanılı hastaların yarısında akut göğüs ağrısı mevcuttur. MVP tanılı hastalardaki bu ağrının tam sebebi bilinmemektedir. Diğer taraftan Nötrofil/Lenfosit oranı (NLO), birçok kardiyovasküler hastalıkta prognoz ve sonuçlar ile ilişkili olduğu bulunmuştur. Bu çalışmada, NLR ile MVP tanılı hastalardaki göğüs ağrısı arasındaki ilişki araştırılmıştır.YÖNTEM ve GEREÇLER: Bu retrospektif çalışmada 2016 ve 2019 yılları arasında enstitümüz kardiyoloji polikliniklerine başvuran MVP tanılı hastaların tıbbi kayıtları incelenmiştir. Göğüs ağrısı ile başvuran MVP tanılı hastaların bazal karakteristikleri, biyokimyasal parametreleri ve NLR değerleri, göğüs ağrısı olmayan MVP tanılı hastalar ( kontrol grup) ile mukayese edilmiştir. MVP tanılı hastalardaki göğüs ağrısının bağımsız belirteçleri lojistik regresyon yöntemi ile araştırılmıştırBULGULAR: Göğüs ağrısı olan MVP tanılı hastalarının vücut kitle endeksleri, Sistolik kan basınçları göğüs ağrısı olmayan MVP hastalarına göre anlamlı olarak daha düşük; kalp hızı, panik atak oranı, kadın cinsiyet, NLO, beyaz küre anlamlı olarak daha yüksek olarak saptandı. Regresyon analizinde, düşük vücut kitle endeksi (OR = 0.76, P

The Neutrophil-To-Lymphocyte Ratio is Associated With Acute Chest Pain in Patients With Mitral Valve Prolapse

ABSTRACTINTRODUCTION: Nearly half of the patients with mitral valve prolapse (MVP) complain of chest pain. The precise cause of chest pain MVP is unknown. On the other side, theneutrophil /lymphocyte ratio (NLR) has been reported to be a useful marker of prognosis and outcomes for many cardiovascular diseases. In this study, we aimed to investigate the relationship between NLR and chest pain in patients with MVP.METHODS: In this retrospective study, we screened medical records of all consecutive patients with MVP applied to outpatient clinics between the years 2016 and 2019 at ourinstitution. Basal characteristics, biochemical parameters, and NLR were compared between the patients with MVP and chest pain and the patients with MVP and without chest pain (control group). Independent predictors of chest pain in MVP patients were determined by logistic regression analysis.RESULTS: The patients with MVP and chest pain had significantly lower body mass index and systolic blood pressure compared to the control group. Heart rate, thenumber of patients with panic disorder, the number of females, NLR, and white blood cell count (WBC) were significantly higher in patients with MVP and chest pain. In the regression analysis, lower body mass index (OR= 0.76, P

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