Şule TAŞ GÜLEN, Onur YAZICI, Altay KANDEMİR

Chronic Obstructive Lung Disease Frequency in Colorectal Polyp and Relationship with Systemic Inflammation

ABSTRACT INTRODUCTION: The prevalence of chronic obstructive pulmonary disease (COPD) in patients with colorectal polyps and its relationship with systemic inflammation was investigated in our study. METHODS: A total of 35 cases with COPD diagnosis (COPD group) and 163 control groups without chronic disease in medical history among patients who were diagnosed colorectal polyposis by colonoscopy between December 2016-December 2017 were included to the study. Demographic data such as age, smoking history, pathology results, anatomic location of the lesion, hemogram data such as leukocyte, neutrophil lymphocyte ratio (NLR) and mean platelet volüme (MPV) were recorded. RESULTS: 137 (69.2%) of the cases were male and the mean age was 63.56 ± 11.68 (20-89) years. Smoking history was available in 129 cases, of which 62 (48.1%) had a smoking history. The prevalence of COPD was 8% among patients with colorectal polyposis in the previous year. Leukocyte, NLR and MPV values were statistical significantly higher in patients with COPD compared to healthy group (p = 0.001,

Kolorektal Polipde Kronik Obstrüktif Akciğer Hastalığı Sıklığı ve Sistemik İnflamasyonla İlişkisi

ÖZ GİRİŞ ve AMAÇ: Çalışmamızda kolorektal polip olgularında Kronik Obstrüktif Akciğer Hastalığı sıklığı (KOAH) ve bu durumun sistemik inflamasyonla ilişkisi araştırılmıştır. YÖNTEM ve GEREÇLER: Aralık 2016 -2017 tarihleri arasında Gastroenteroloji kliniğinde kolonoskopi yapılan ve kolorektal polipozis tanısı konulan olgulardan özgeçmiş sorgulamasında KOAH tanısı olan 35 olgu ile yine özgeçmiş sorgulamasında herhangi bir kronik hastalığı olmayan 163 kontrol olgu alındı. Tüm olguların yaş, sigara öyküsü (paketyıl) gibi demografik verileri, patoloji sonuçları, lezyonun anatomik yeri ile lökosit, nötrofil lenfosit oranı (NLO) ve ortalama trombosit hacmi (MCV) parametrelerinden oluşan hemogram verileri kaydedildi. BULGULAR: Olguların 137 (%69,2)’si erkek, 61 (%30,8)’i kadın ve yaş ortalaması 63,56±11,68 (20-89) olarak bulundu. 129 olgunun sigara öykülerine ulaşılabildi ve bunlardan 62 (%48,1)’sinin sigara öyküsü vardı. Son 1 yılda kolorektal polipozis tanısı konulan olgular arasında KOAH sıklığı %8 olarak bulundu. KOAH olanlarda kontrol grubuna göre lökosit, NLO ve MCV değerleri istatistiksel olarak anlamlı olarak daha yüksek bulundu (sırasıyla p= 0,001,

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