Nonfonksiyonel Hipofiz Adenomlarının Cerrahi Endikasyonları ve Yönetimi

Aktif hormon sekresyonu yapmayan hipofiz tümörleri nonfonksiyonel adenom olarakadlandırılmaktadır. Tüm hipofiz adenomları içerisindeki oranları %30-35’dir. Bunlarınekseriside (%80-90) gonodotropik adenomlar tarafından oluşturulmaktadır. Hastalargenellikle nörolojik semptomlar ya da hipofizer yetmezlik şeklinde klinik gösterirler.Nonfonksyonel adenomu bulunan hastaların tedavisindeki amaçlar; nörolojik semptomlarındüzeltilmesi, nükse müsaade etmeyecek şekilde mümkünse makroadenom dokusununtamamen çıkartılması ve normal hipofiz dokusunun basısı sonucu gelişen hormonalyetmezliğin yönetimidir.

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