Ufuk ÖZGÜL, Hakan GÜNEŞ, Bayram ÖZTÜRK, Ahmet YILMAZ

Koroner Arter Hastalığı Yaygınlığı’nın RDW ile İlişkisi

Amaç: Bu çalışmanın amacı akut koroner sendromlu (AKS) hastalarda aterosklerotik hastalığın yaygınlığını göstermek için kullanılan GENSİNİ skoru ile eritrosit dağılım hacmi arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntemler: Çalışmaya AKS tanısı ile koroner anjiografi işlemi yapılan 359 hasta alındı. Hastaların anjiografik görüntüleri analiz edilerek GENSİNİ skorları hesaplandı. Hastalar GENSİNİ skoru<20 ve ≥ 20 olmak üzere iki gruba ayrıldı. Bu iki grubun demografik, klinik ve labaratuvar parametreleri karşılaştırıldı ve GENSİNİ skor yüksekliğini predikte eden değerler araştırıldı. Bulgular: Çalışmaya dahil edilen 359 hastanın 104 kadın hasta, 255 erkekti. GENSİNİ skoru <20 olan hastası sayısı 69 iken, GENSİNİ skoru ≥20 olan hasta sayısı 290 idi.Eritrosit Dağılım Genişliğinin (RDW) GENSİNİ SKORU ≥20 olan grupta daha yüksek olduğu görüldü.( 13.7±0.9 ve 14.2±1.4 p=0.001).Yapılan korelasyon analizinde RDW ile GENSİNİ skoru arasında pozitif korelasyon izlendi (r :0.137 p.009).Yapılan multivaryant analizde RDW nin GENSİNİ skorunun bağımsız prediktörü olduğu görüldü.( OR:1.417, %95 CI(1.037-1.935) p= 0.029) Sonuç: AKS ile başvuran hastalarda kolay ve ulaşılabilir bir parametre olan RDW atreosklerotik kalp hastalığının şiddeti ile korele olup aterosklerotik kalp hastalığının prediktörü olarak kullanılabilir

Anahtar Kelimeler:

AKS, RDW, GENSİNİ SKORU

Relationship Between Coronary Artery Disease Prevelance and RDW Levels

Objective: The aim of this study is to investigate the relationship between the GENSINI score used to show the prevalence of atherosclerotic disease in patients with acute coronary syndrome (ACS) and the red blood cell distribution volume. Material and Methods: 359 patients with a diagnosis of ACS who underwent coronary angiography were included in the study. The patients were divided into two groups as GENSINI score <20 and> 20, by analyzing their angiographic images. The demographic, clinical and laboratory parameters of these two groups were compared and the values predicting the GENISI score high were investigated. Results: Of the 359 patients included in the study, 104 female patients were 255 men. While the number of patients with a GENSINI score of < 20 was 69, the number of patients with a GENSINI score of ≥20 was 290. It was observed that Red Cell Distribution Width (RDW) value was higher in the group with GENSINI score> 20 (13.7 ± 0.9 and 14.2 ± 1.4 p = 0.001). In the correlation analysis, a positive correlation was observed between RDW and GENSINI score (r: 0.137 p.009).RDW was seen to be the independent predictor of the GENSINI score. (OR: 1.417, 95% CI (1.037-1.935) p = 0.029) Conclusion: RDW, which is an easy and accessible parameter in patients presenting with ACS, correlates with the severity of atherosclerotic heart disease and can be used as a predictor of atherosclerotic heart disease.

Keywords:

ACS, RDW, GENSİNİ SCORE,

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